Results 51 to 60 of about 16,408 (183)

Improvement of Interferon-Beta Production in Transient Expression System of CHO DG44 by a Codon Bias Change in Instability Sequence (CRID) of C-terminal of Interferon Beta Gene

مجله دانشکده پزشکی اصفهان, 2012
Background: Improvement of mRNA stability and therefore, production of interferon beta (IFNb) in Chinese hamster ovary (CHO) cell, as a recombinant protein expression system, is very important.
Zahra Bezi, Hassan Korbekandi, Batool Hashemibeni, Zohreh Hojjati, Amin Moradi Hassanabad, Mohammad Reza Marasi   +5 more
doaj  

High‐yield, plant‐based production of an antimicrobial peptide with potent activity in a mouse model

Plant Biotechnology Journal, Volume 22, Issue 12, Page 3392-3405, December 2024.
Summary Plants offer a promising chassis for the large‐scale, cost‐effective production of diverse therapeutics, including antimicrobial peptides (AMPs). However, key advances will reduce production costs, including simplifying the downstream processing and purification steps.
Shahid Chaudhary, Zahir Ali, Aarón Pantoja‐Angles, Sherin Abdelrahman, Cynthia Olivia Baldelamar Juárez, Gundra Sivakrishna Rao, Pei‐Ying Hong, Charlotte Hauser, Magdy Mahfouz   +8 more
wiley   +1 more source

Characterization of the Ubiquitin‐Modified Proteome of Recombinant Chinese Hamster Ovary Cells in Response to Endoplasmic Reticulum Stress

Biotechnology Journal, Volume 19, Issue 11, November 2024.
Graphical Abstract and Lay Summary Ubiquitination is an essential cellular process in which proteins are tagged with ubiquitin, marking them for proteasomal degradation. Beyond this role, ubiquitination plays key functions in ER stress, cell signalling, autophagy, and cell cycle regulation. To gain deep insights into ER stress mechanisms and changes to
Karuppuchamy Selvaprakash, Christiana‐Kondylo Sideri, Michael Henry, Esen Efeoglu, David Ryan, Paula Meleady   +5 more
wiley   +1 more source

KLOTHO protein sequences (sixteen species) FULL DATASET

, 2014
Genomic data & Amino Acid composition  Including: Heterocephalus glaber, Chinchilla lanigera, Ochotona princeps, Mus musculus, Rattus norvegicus, Mesocricetus auratus, Peromyscus maniculatus bairdii, Microtus ochrogaster, Chrysochloris asiatica ...
Tommy Rodriguez (459995)
core   +1 more source

Chinese hamster ovary cell line engineering strategies for modular production of custom extracellular vesicles

Biotechnology and Bioengineering, Volume 121, Issue 9, Page 2907-2923, September 2024.
Abstract Continuously secreted by all cell types, extracellular vesicles (EVs) are small membrane‐bound structures which shuttle bioactive cargo between cells across their external environment. Their central role as natural molecular messengers and ability to cross biological barriers has garnered significant attention in the use of EVs as therapeutic ...
Braulio Carrillo Sanchez, Matthew Hinchliffe, Mark Ellis, Catherine Simpson, David Humphreys, Bernie Sweeney, Daniel G. Bracewell   +6 more
wiley   +1 more source

Metabolomic characterization of monoclonal antibody‐producing Chinese hamster lung (CHL)‐YN cells in glucose‐controlled serum‐free fed‐batch operation

Biotechnology and Bioengineering, Volume 121, Issue 9, Page 2848-2867, September 2024.
The authors applied a novel fast‐proliferating cell line, Chinese hamster lung (CHL)‐YN, to the monoclonal antibody production by developing glucose control strategies for serum‐free fed‐batch cultivation and then studying their metabolic profiles.
Puriwat Sukwattananipaat, Hirotaka Kuroda, Noriko Yamano‐Adachi, Takeshi Omasa   +3 more
wiley   +1 more source

KLOTHO phylogeny diagram (sixteen sequences)

, 2014
[protein sequences] reverse translation [nucleotide sequences] Including: Heterocephalus glaber, Chinchilla lanigera, Ochotona princeps, Mus musculus, Rattus norvegicus, Mesocricetus auratus, Peromyscus maniculatus bairdii, Microtus ochrogaster ...
Tommy Rodriguez (459995)
core   +1 more source

SARS-CoV-2 infection of Chinese hamsters (Cricetulus griseus) reproduces COVID-19 pneumonia in a well-established small animal model. [PDF]

Transbound Emerg Dis, 2021
Bertzbach LD, Vladimirova D, Dietert K, Abdelgawad A, Gruber AD, Osterrieder N, Trimpert J.   +6 more
europepmc   +1 more source

Inability of styrene to induce nondisjunction in Drosophila or a positive micronucleus test in the Chinese hamster

, 1980
Styrene produced no effect on induction of sex-chromosome nondisjunction in Drosophila melanogaster fed on 500 ppm styrene for 24 h. No increase in the frequency of micronuclei from chromosome fragments or from nondisjunction of whole chromosomes was ...
Sorsa, Marja, Vainio, Harri, Penttilä, Merja; id_orcid   +2 more
core   +1 more source

Fig 6, aBSREL Data Monkey Analysis Results for NLRC4 Protein.

, 2022
Fig 6, aBSREL Data Monkey Analysis Results for NLRC4 Protein. Six Aligned DNA coding sequences were taken from the NLRC4 FASTA file with stop codons excluded.
Dylan Hart (12218678), Ryan Luedtke (12214127), Ean Chalfie (12236018)   +2 more
core   +1 more source