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Crimean-Congo Hemorrhagic Fever Virus: An Emerging Threat in Europe with a Focus on Epidemiology in Spain. [PDF]

Pathogens
Eslava M, Carlos S, Reina G.
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Crimean-Congo Hemorrhagic Fever Virus

Current Molecular Medicine, 2005
Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen, which is the cause of a tick-borne illness occurring in many areas of Africa, Asia, and Europe. CCHF is characterized by a sudden onset of high fever, chills, and severe headache.
Ramon, Flick, Chris A, Whitehouse
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Crimean-Congo Hemorrhagic Fever Virus in Pakistan

Infectious Disorders - Drug Targets, 2017
The Crimean-Congo hemorrhagic fever is a zoonotic disease transmitted by ticks and is characterized by fever and bleeding. It was seen for the first time in the south of present day Ukraine and thus named, Crimean fever. 1 In 1956, the virus was isolated in a patient with similar symptoms residing in Congo, Kenya and the virus was named Congo virus ...
Muhammad, Ijaz, Afaq, Rahim, Iftikhar, Ali   +2 more
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Parotitis associated with Crimean Congo hemorrhagic fever virus

Journal of Clinical Virology, 2012
Crimean Congo Hemorrhagic Fever (CCHF) is a potentially fatal tick-borne viral disease, the course of which may accompanied by various clinical findings.We describe a picture of non-suppurative parotitis developing in association with CCHF virus.A 48-year-old patient presenting to our hospital with lethargy, hemorrhage and pain and swelling below the ...
Selçuk, Kaya, Gurdal, Yilmaz, Barış, Ertunç, Iftihar, Koksal   +3 more
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Cytokine response in crimean‐congo hemorrhagic fever virus infection

Journal of Medical Virology, 2017
We described the predictive role of cytokines in fatality of Crimean Congo Hemorrhagic Fever Virus (CCHFV) infection by using daily clinical sera samples. Consequent serum samples of the selected patients in different severity groups and healthy controls were examined by using human cytokine 17‐plex assay.
Önder Ergönül, Ceren Şeref, Şebnem Eren, Aysel Çelikbaş, Nurcan Baykam, Başak Dokuzoğuz, Mehmet Gönen, Füsun Can   +7 more
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Exogenous nitric oxide inhibits Crimean Congo hemorrhagic fever virus

Virus Research, 2006
Crimean Congo hemorrhagic fever virus (CCHFV) is a geographically widespread pathogen that causes severe hemorrhagic fever with high mortality. Even though one of the main objectives focuses on the progress of antiviral agents, the research on CCHFV is strongly hampered due to its BSL-4 classification.
M, Simon, K I, Falk, A, Lundkvist, A, Mirazimi   +3 more
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Diagnostic approaches for Crimean-Congo hemorrhagic fever virus

Expert Review of Molecular Diagnostics, 2019
Introduction: Crimean-Congo hemorrhagic fever (CCHF) is a potentially severe tick-borne viral disease endemic in several regions of Europe, Africa, and Asia. Rapid and reliable diagnosis is essential for early initiation of patient's treatment and for prompt implementation of appropriate precaution and infection control measures to prevent further ...
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Ancient common ancestry of Crimean-Congo hemorrhagic fever virus

Molecular Phylogenetics and Evolution, 2010
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne RNA virus responsible for outbreaks of severe hemorrhagic fever in humans. Although CCHF was first detected in the 1940s, high levels of genomic diversity argue against a recent origin. Here, Bayesian coalescent analyses were used to estimate the rate of evolution and relative age of the virus.
Serena A, Carroll, Brian H, Bird, Pierre E, Rollin, Stuart T, Nichol   +3 more
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Crimean–Congo Hemorrhagic Fever Virus

2006
Publisher Summary Crimean–Congo hemorrhagic fever (CCHF) is a member of the Nairovirus genus of the Bunyaviridae family. CCHFV is a single-stranded RNA virus, with a genome consisting of three negative-stranded segments designated S (small), M (medium), and L (large), which encode the nucleocapsid (N) protein, two envelope glycoproteins (G1 and G2 ...
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Crimean–Congo hemorrhagic fever virus: new outbreaks, new discoveries

Current Opinion in Virology, 2012
Crimean-Congo hemorrhagic fever (CCHF) is a fatal viral infection described in Asia, Africa and Europe. Humans become infected through the bites of ticks, by contact with a patient with CCHF during the acute phase of infection, or by contact with blood or tissues from viremic livestock.
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