Results 221 to 230 of about 10,763 (250)

Crimean–Congo Hemorrhagic Fever Virus

, 2006
Publisher Summary Crimean–Congo hemorrhagic fever (CCHF) is a member of the Nairovirus genus of the Bunyaviridae family. CCHFV is a single-stranded RNA virus, with a genome consisting of three negative-stranded segments designated S (small), M (medium), and L (large), which encode the nucleocapsid (N) protein, two envelope glycoproteins (G1 and G2 ...
P. Nabeth
semanticscholar   +2 more sources

Evolution of Crimean-Congo Hemorrhagic Fever virus

Infection, Genetics and Evolution, 2009
The evolutionary patterns of each genome RNA segment of Crimean-Congo Hemorrhagic Fever virus (CCHFV) were investigated. Nucleotide sequences from 40 CCHFV strains isolated during time period spanning from 1956 to 2003 were tested. It was found that there is not any global molecular clock ticking at the same rate for CCHFV strains; however a local ...
Anna Papa
exaly   +3 more sources

Crimean-Congo Hemorrhagic Fever Virus in Pakistan

Infectious Disorders - Drug Targets, 2017
The Crimean-Congo hemorrhagic fever is a zoonotic disease transmitted by ticks and is characterized by fever and bleeding. It was seen for the first time in the south of present day Ukraine and thus named, Crimean fever. 1 In 1956, the virus was isolated in a patient with similar symptoms residing in Congo, Kenya and the virus was named Congo virus ...
Muhammad, Ijaz, Afaq, Rahim, Iftikhar, Ali   +2 more
openaire   +2 more sources

Diagnostic approaches for Crimean-Congo hemorrhagic fever virus

Expert Review of Molecular Diagnostics, 2019
Introduction: Crimean-Congo hemorrhagic fever (CCHF) is a potentially severe tick-borne viral disease endemic in several regions of Europe, Africa, and Asia. Rapid and reliable diagnosis is essential for early initiation of patient's treatment and for prompt implementation of appropriate precaution and infection control measures to prevent further ...
Anna Papa
exaly   +3 more sources

The impact of Crimean-Congo hemorrhagic fever virus on public health

Antiviral Research, 2013
Climatic, environmental and economic changes, as well as the steadily increasing global trade and personal mobility provide ample opportunities for emerging pathogens with zoonotic potential to spread to previously unaffected countries. Crimean-Congo hemorrhagic fever virus (CCHFV) is considered to be one of the major emerging disease threats spreading
Marc Mertens, Katja Schmidt, Aykut Ozkul   +2 more
exaly   +3 more sources

Epidemiology of the Crimean-Congo hemorrhagic fever virus

Acta Tropica
Crimean-Congo hemorrhagic fever virus (CCHFV) is endemic in >30 countries across Asia, Europe, the Middle East, and Africa. CCHFV causes Crimean-Congo hemorrhagic fever (CCHF), a disease characterized by bleeding and haemoptysis. Since the first diagnosis in 1944, 10,000-15,000 CCHF cases are reported worldwide annually. Around three billion people are
Neha Kaushal, Sahil Jain, Dimple Davray, Albert Rizvanov, Ming-Hsien Chiang, Olesia Ohlopkova, Svetlana Khaiboullina, Ze Chen, Manoj Baranwal   +8 more
openaire   +2 more sources

Parotitis associated with Crimean Congo hemorrhagic fever virus

Journal of Clinical Virology, 2012
Crimean Congo Hemorrhagic Fever (CCHF) is a potentially fatal tick-borne viral disease, the course of which may accompanied by various clinical findings.We describe a picture of non-suppurative parotitis developing in association with CCHF virus.A 48-year-old patient presenting to our hospital with lethargy, hemorrhage and pain and swelling below the ...
Selçuk, Kaya, Gurdal, Yilmaz, Barış, Ertunç, Iftihar, Koksal   +3 more
openaire   +2 more sources

Single dose VSV-based vaccine protects mice against lethal heterologous Crimean-Congo hemorrhagic fever virus challenge

npj Vaccines
Crimean-Congo hemorrhagic fever virus (CCHFV) causes a severe, sometimes fatal hemorrhagic fever (CCHF) in humans. Currently, there are no approved therapies against CCHF. In this study we used the recombinant vesicular stomatitis virus (VSV) platform to
Thomas Tipih, Shanna S. Leventhal, Kimberly Meade-White, Matthew C. Lewis, T. Bushmaker, Carl I. Shaia, A. Marzi, H. Feldmann, David W. Hawman   +8 more
semanticscholar   +1 more source

Cytokine response in crimean‐congo hemorrhagic fever virus infection

Journal of Medical Virology, 2017
We described the predictive role of cytokines in fatality of Crimean Congo Hemorrhagic Fever Virus (CCHFV) infection by using daily clinical sera samples. Consequent serum samples of the selected patients in different severity groups and healthy controls were examined by using human cytokine 17‐plex assay.
Önder Ergönül, Ceren Şeref, Şebnem Eren, Aysel Çelikbaş, Nurcan Baykam, Başak Dokuzoğuz, Mehmet Gönen, Füsun Can   +7 more
openaire   +3 more sources

Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21

Nature Communications
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a negative-sense RNA virus spread by Hyalomma genus ticks across Europe, Asia, and Africa. CCHF disease begins as a non-specific febrile illness which may progress into a severe hemorrhagic disease with no
Shanna S. Leventhal, Thomas Bisom, D. Clift, Deepashri Rao, Kimberly Meade-White, Carl I. Shaia, Justin Murray, E. Mihalakakos, Troy Hinkley, Steven J Reynolds, Sonja M. Best, Jesse H. Erasmus, Leo C. James, H. Feldmann, David W. Hawman   +14 more
semanticscholar   +1 more source