Results 141 to 150 of about 4,533,202 (342)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Enhancing Employee Communication Behaviors for Sensemaking and Sensegiving in Crisis Situations: Strategic Management Approach for Effective Internal Crisis Communication [PDF]
, 2018 Purpose The purpose of this paper is to explore the organizational effectiveness of internal crisis communication within the strategic management approach, whether it enhanced voluntary and positive employee communication behaviors (ECBs) for sensemaking
Kim, Young
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Framing the housing crisis: How think-tanks frame politics and science to advance policy agendas
, 2022 Chris Foye
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Nascent island tourism policy development in Greenland: A network perspective
Island Studies Journal, 2019 Following its achievement of Self-Rule status in 2009 Greenland embarked on a series of measures to diversify its economy with an eye towards eventually gaining full independence from Denmark. Tourism was underlined as a key sector for reaching this goal
Evangelia Petridou +2 more
doaj +1 more source
Banking Union: How stable are Europe’s banks? EUROPA Briefing 2017 [PDF]
, 2017 The euro crisis was, besides an economic and sovereign debt crisis, a full-blown banking crisis. The Banking Union was thus created precisely to break the vicious circle of ailing banks and weak government finances in the Eurozone.
Ständer, Philipp
core
Determinants of European Banks’ Bailouts Following the 2007–2008 Financial Crisis [PDF]
, 2016 Catarina Fernandes +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source