Results 151 to 160 of about 4,257,137 (288)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Nepal: Responding to the Royal Coup [PDF]

open access: yes, 2005
International Crisis Group
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Nepal: Peace Postponed [PDF]

open access: yes, 2007
International Crisis Group
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Accuracy of New Hypertensive Crisis Diagnoses Using International Classification of Disease (ICD)-10: A Validation Study in a National Medicare Sample. [PDF]

open access: yesJ Clin Hypertens (Greenwich)
Visaria A   +12 more
europepmc   +1 more source

Nepal: From People Power to Peace? [PDF]

open access: yes, 2006
International Crisis Group
core  

Home - About - Disclaimer - Privacy