Results 61 to 70 of about 5,358,439 (388)
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
The Changing Opioid Crisis: development, challenges and opportunities
The current opioid epidemic is one of the most severe public health crisis in US history. Responding to it has been difficult due to its rapidly changing nature and the severity of its associated outcomes. This review examines the origin and evolution of
N. Volkow, C. Blanco
semanticscholar +1 more source
Sanitary Crisis, Civilizational Crisis [PDF]
Sanitary Crisis, Civilizational Crisis is the translation of Michel Maffesoli’s Crise sanitaire, crise civilisationnelle. This paper can be taken as his pronouncement on the civilizational crisis that the COVID-19 pandemic acutely reveals. Maffesoli’s text urges one to see beyond secondary causes or dramatic representations of the pandemic as a ...
openaire +3 more sources
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
The COVID-19 outbreak is a global crisis that has placed small and medium enterprises (SMEs) under huge pressure to survive, requiring them to respond effectively to the crisis.
Hai Guo, Zhuen Yang, Ran Huang, Anqi Guo
semanticscholar +1 more source
The Theory Crisis in Psychology: How to Move Forward
Meehl argued in 1978 that theories in psychology come and go, with little cumulative progress. We believe that this assessment still holds, as also evidenced by increasingly common claims that psychology is facing a “theory crisis” and that psychologists
M. Eronen, L. Bringmann
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
THE PROBLEM OF QUALITY OF THE FINANCIAL ANALYSIS IN INSOLVENCY (BANCRUPTCY) PROCEDURES
It examines the role of financial analysis in the contemporary system of insolvency management, based on many years of practical experience, explores the сauses of poor quality of analytical procedures and the typical shortcomings of financial ...
N. G. Akulova, D. I. Ryakhovsky
doaj +1 more source
The Interpersonal Style and Complementarity Between Crisis Negotiators and Forensic Inpatients [PDF]
Previous negotiation research has explored the interaction and communication between crisis negotiators and perpetrators. A crisis negotiator attempts to resolve a critical incident through negotiation with an individual, or group of persons in crisis ...
A Dolink +24 more
core +1 more source
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source

