Results 111 to 120 of about 10,303,282 (310)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Designing EU Crisis Management Capacities: Filling the Glass

, 2014
The European Union (EU) has modest but promising capacities to assist member states overwhelmed by disaster through its Civil Protection Mechanism. The EU also routinely sends civil and military missions to hotspots outside EU territory.
Magnus Ekengren, Fulvio Attinà, Attina, Fulvio, Public Management, Ekengren, Magnus,, Arjen Boin, Attina, Fulvio,, LS Bestuurkunde, UU LEG Research USG Public Matters Public Governance and Management, Boin, Arjen, Boin, Arjen,, Ekengren, Magnus   +11 more
core   +1 more source

Zero Events, Limited Precision, and the Interpretation of Olanzapine Safety in Patients with Diabetes Receiving Cisplatin [Response to Letter]

Drug Design, Development and Therapy
Toshinobu Hayashi,1 Chihiro Shiraishi,1 Masakazu Abe,2 Susumu Kaneshige,3 Takashi Egawa11Department of Pharmaceutical Sciences for Health Crisis Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; 2Department of Obstetrics
Hayashi T, Shiraishi C, Abe M, Kaneshige S, Egawa T   +4 more
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Crisis Management [PDF]

Anaesthesia and Intensive Care, 1988
openaire   +2 more sources

Safety of Short-T erm Low-Dose Olanzapine in Patients with Cancer and Diabetes Receiving Cisplatin-Based Chemotherapy: A Retrospective TriNetX Cohort Study

Drug Design, Development and Therapy
Toshinobu Hayashi,1,* Chihiro Shiraishi,1,* Masakazu Abe,2 Susumu Kaneshige,3 Takashi Egawa11Department of Pharmaceutical Sciences for Health Crisis Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan ...
Hayashi T, Shiraishi C, Abe M, Kaneshige S, Egawa T   +4 more
doaj  

Effects of Urban Space Limitations on the Performance of Firefighting Forces and Vehicles During a Disaster in Tehran, District 19 [PDF]

دانش پیشگیری و مدیریت بحران
Background and objective To reduce the risks of fire accidents, it is essential to analyze space-time constraints for firefighters. In district 19 of Tehran city, Iran, the spatio-temporal patterns of fires vary depending on time, location, and causes ...
Afrasyab Kheirdast, Mahdi Mahdavi, Saeed Ajourloo   +2 more
doaj  

Rail Freight Transport Market Liberalization After Two Decades of Its Beginning

Journal of Advanced Transportation
It has been almost 2 decades since the opening of the rail freight market in the EU came into force. The individual Member States have put different liberalization measures into practice, and the situation on the market still varies from country to ...
Igor Domeny
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Lessons from the Current Financial Crisis. A Risk Management Approach [PDF]

In the last twenty years, the financial risk management has gained an important role for the companies and financial institutions. Financial innovations have improved the efficiency of risk management process, but at the same time, they have imposed new ...
Gheorghe VOINEA, Sorin Gabriel ANTON
core