Results 111 to 120 of about 1,649,859 (246)
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
THE CRISIS AND THE COST MANAGEMENT [PDF]
The aim of the present study is the analysis of the phenomenon of contemporary crisisand its unfavourable effects upon the global economy, in general, and the developing countries, inparticular. It also has in view the most appropriate decisions that the
Florentina Sas, Sorin Briciu
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Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Deterring a Nuclear Iran: The Devil in the Details [PDF]
, 2010 Explores the technical requirements for a deterrence regime against Iran should it acquire a nuclear weapons capability. Considers red lines, treaty arrangements, force deployment and bases, military assistance to Iran's neighbors, and crisis ...
Kenneth M. Pollack
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Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
THE CONSEQUENCES OF THE FINANCIAL CRISIS UPON EMERGING AND DEVELOPPING COUNTRIES [PDF]
The authors of the research analyze the impact and the effects of the financial crisis upon the emerging and developing countries. Moreover, the impact of the international economic crisis upon the new member states of the European Union has proved to be
Anca Mirela POSTOLE +2 more
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Crisis Prevention and Management - What Worked in the 2008/2009 Crisis? [PDF]
This paper takes a systematic look at the economic impact of the crisis that started in earnest in the fall of 2008 across countries and regions. Despite warnings of growing domestic and external imbalances in many countries years ahead of the crisis ...
Becker, Torbjörn
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The Strategic Role of Human Resources Development in the Management of Organizational Crisis [PDF]
Together with the global economic crisis, the impact of organizational crises on human capital and its performances has become increasingly obvious. From this perspective, the strategic role of human resources’ development is crucial, being analyzed in ...
Cristina ALPOPI +2 more
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