Results 91 to 100 of about 10,303,282 (310)

Seizing Europe - – Crisis Management, Constitutional Transformations, Constituent Movements

open access: yes, 2013
The essay highlights some aspects of the new political situation in Europe in the wake of the global economic crisis, particularly focusing on the resulting consequences for such important political and legal concepts as citizenship and constitution.
MEZZADRA, SANDRO
core   +1 more source

EVALUATION OF THE FINANCIAL POSITION OF THE ENTERPRISE AND DETERMINATION OF THE OPTIMAL MODEL OF THE PROBABILITY OF BANKRUPTCY

open access: yesСтратегические решения и риск-менеджмент, 2015
The article deals with the financial analysis of the companies in bankruptcy proceedings. Using the principle of invariance of factors in predicting the functions of financial analysis, it was possible to assess the parameters and structure of the ...
A. V. Babanov
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Socio-Technical Design Approach for Crisis Management Information Systems

open access: yes, 2009
This article describes research in progress of a design approach for crisis management information systems. A qualitative study was designed to gather data from four municipalities in northern Sweden, which all have responsibility for crisis management ...
John Lindström   +5 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Managing Crisis in the Eurozone

open access: yesPolitička misao : časopis za politologiju, 2011
Euro crisis displayed its full blow in the spring of 2010. Its dynamics revealed deep-seated structural flaws at the core of the EMU. The productive Germany is tied via the euro currency union to countries that have lower productivity rates and inefficient economies.
Brkić, Luka, Kotarski, Kristijan
openaire   +4 more sources

Preliminary Evaluation of Pooled Respirometry for Estimating Oxygen Consumption in the Freshwater Shrimp Neocaridina denticulata (Crustacea: Decapoda: Atyidae)

open access: yesHydrobiology
Metabolic rate is closely linked to body mass and is widely used to relate physiological processes to ecological and evolutionary patterns. In small aquatic organisms, measurements of oxygen consumption rate (Mo2) are often limited by instrument ...
Dong In Kim   +2 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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