Results 71 to 80 of about 1,649,859 (246)

Implementation Maturity Levels of Digital Twin Technology and Data Content Design for Flood Digital Twin

open access: yesSmart Cities
This study examines the potential of digital twin (DT) technology to strengthen urban security, with a specific focus on flood risk management in smart cities.
Jozef Ristvej   +3 more
doaj   +1 more source

Putting out the Cerro Grande fire: a case study in government crisis communication [PDF]

open access: yes, 2003
In 2000, the U.S. National Park Service (NPS) initiated a prescribed burn, which went awry, prompting New Mexico's largest wildfire to date. This paper examines the NPS’s crisis response in an effort to determine its media response, how that response ...
Darmon, Keren, Romo, Lara
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Has the Basel II Accord Encouraged Risk Management During the 2008-09 Financial Crisis? [PDF]

open access: yes
The Basel II Accord requires that banks and other Authorized Deposit-taking Institutions (ADIs) communicate their daily risk forecasts to the appropriate monetary authorities at the beginning of each trading day, using one or more risk models to measure ...
Juan-Ángel Jiménez-Martín   +2 more
core   +6 more sources

A Component-Based Approach to Early Warning Systems: A Theoretical Model

open access: yesApplied Sciences
Natural hazards pose an increasing threat to society, necessitating the development of effective early warning systems (EWSs). This paper explores their critical role in mitigating the impacts of natural hazards.
Daniel Chovanec   +5 more
doaj   +1 more source

Complex Model of Risk Assessment of Industrial Processes Mopori

open access: yesCommunications, 2013
Modern day society wants to create optimal living conditions for its citizens and to ensure constant sustainable development. This objective cannot be achieved without reaching the required level of perceived security in complex.
Katarina Holla   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

EVALUATION OF THE FINANCIAL POSITION OF THE ENTERPRISE AND DETERMINATION OF THE OPTIMAL MODEL OF THE PROBABILITY OF BANKRUPTCY

open access: yesСтратегические решения и риск-менеджмент, 2015
The article deals with the financial analysis of the companies in bankruptcy proceedings. Using the principle of invariance of factors in predicting the functions of financial analysis, it was possible to assess the parameters and structure of the ...
A. V. Babanov
doaj   +1 more source

Financial Crisis and Crisis Management in Sweden. Lessons for Today [PDF]

open access: yes
This paper gives an account of the Swedish financial crisis covering the period 1985–2000, dealing with financial deregulation and the boom in the late 1980s, the bust and the financial crisis in the early 1990s, the recovery from the crisis and the bank
Jonung, Lars
core   +1 more source

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