Results 71 to 80 of about 10,303,282 (310)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

ANALYSIS OF LAW ON LIMITED USE (SERVITUDE) OF A LAND PLOT

Стратегические решения и риск-менеджмент, 2014
The article makes an attempt to analyze proprietary rights on land, to compare legal regulations on forming a land plot and registering it in Russia. System characteristics are studied: rights on a land plot, land plot definition, possible versions of ...
E. A. Voronova, I. A. Tedoradze
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A Component-Based Approach to Early Warning Systems: A Theoretical Model

Applied Sciences
Natural hazards pose an increasing threat to society, necessitating the development of effective early warning systems (EWSs). This paper explores their critical role in mitigating the impacts of natural hazards.
Daniel Chovanec, Boris Kollár, Bronislava Halúsková, Jozef Kubás, Marcin Pawęska, Jozef Ristvej   +5 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Financial Crisis and Crisis Management in Sweden. Lessons for Today [PDF]

This paper gives an account of the Swedish financial crisis covering the period 1985–2000, dealing with financial deregulation and the boom in the late 1980s, the bust and the financial crisis in the early 1990s, the recovery from the crisis and the bank
Jonung, Lars
core  

A New European Settlement Map From Optical Remotely Sensed Data

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2016
An application of a general methodology for processing very high-resolution imagery to produce a European Settlement Map (ESM) in support of policy-makers is presented. The process mapped around 10 million km2 of the European continent.
Aneta Jadwiga Florczyk, Stefano Ferri, Vasileios Syrris, Thomas Kemper, Matina Halkia, Pierre Soille, Martino Pesaresi   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Financial Crisis Inquiry Commission

, 2011
This website contains the research and final report for the Financial Crisis Inquiry Commission looking at the causes of the economic ...
United States. Financial Crisis Inquiry Commission.
core  

Adaptive strategizing : The role of affective expressions for effective crisis management

, 2015
This study sets out to investigate the role of affectivity in crisis management groups and its connection to effective crisis management. We studied the affective reactions in 23 crisis management groups in a major global corporation that participated in
Brundin, Ethel, Netz, Joakim,, Brundin, Ethel,, Svensson, Martin,, Netz, Joakim   +4 more
core   +1 more source