Results 51 to 60 of about 322,656 (316)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Environmental Health and Preventive MedicineBackground: Mass gatherings during the peak summer months pose a notable risk for heat-related illnesses due to extreme heat and humidity. We aimed to identify trends in preventive measures taken against heat-related illnesses at mass gathering rock ...
Asuka Takeda +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Analysis of the Risks of Small and Medium-Sized Enterprises in the Zilina Region
Communications, 2015 Small and medium-sized enterprises (SMEs) are very sensitive to changes in the business environment which after a certain time are always reflected into quantitative characteristics of this sector. In 2013, we accomplished a statistical survey on current
Maria Hudakova +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
, 2013 International audienceWhile current crisis management literature focuses on the necessity of consistent data and shared interpretation to coordinate effectively, contrastingly, this paper highlights the predominating influence of crisis responders ...
Adrot, Anouck, Moriceau, Jean-Luc
core +1 more source
, 2022 This article draws attention to the social context and working methods in crisis management. Based on 1000 interviews with business leaders in Swedish small- and medium-sized enterprises (SMEs), we analyze crisis management in practice and ask: What ...
Elliot, Viktor, +5 more
core +1 more source
Integration of investment strategies in the system of strategic planning of territorial development
Управление, 2019 The issues of legal regulation of investment activity at the level of the Federation entities of the Russian Federation have been considered. The purpose of the research is the study of strategic documents in the field of investment activities of the ...
O. V. Kozhevina
doaj +1 more source