Results 61 to 70 of about 12,146 (263)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Humanities: an Unfinished Project
Teksty Drugie, 2015 Discussing four contemporary approaches to the humanities, those expressed by Marquard, Nussbaum, Rorty, and Fish, the author takes the side of those who believe that humanities have a political impact on society, regardless of what liberal partisans of ...
Michał Paweł Markowski
doaj
Strategies for the development of humanities education in the age of technocratism and globalization
Філософія освіти, 2020 The article is devoted to the study of basic strategies for the development of humanities education in the technocratic and global world. It is stated that total pragmatism and technocratism of our lives causes a deep crisis of study of humanities and ...
Nataliia Petruk
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Numeracy, 2016 Sydney Siegel and N. John Castellan, Jr. Nonparametric Statistics for the Behavioral Sciences, Second Edition (New York NY: McGraw Hill, 1988). 399 pp. ISBN: 9780070573574.
Paul H. Grawe
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Humanities, 2020 There are available by now many arguments concerning the intrinsic and endemic value of the humanities, and both from a medievalist and a modernist perspective.
Albrecht Classen
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Vpliv gospodarskih razmer na zaposlovanje diplomantov
Economic and Business Review, 2019 During the recent economic crisis, new generations of college graduates have entered the labor market each year facing lower labor demand, which has severely affected their transition into the labor market.
Daša Farčnik, Polona Domadenik
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