Results 61 to 70 of about 19,765 (302)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Clinical Ethics in the Context of Medical Humanities
, 2022 Medical humanities are vital for increasing clinical effectiveness. There is a crisis in medicine and bioethics as the epistemological status of medicine has been challenged and the goals of healthcare are often in tension.
Picozzi M., Nicoli F.
core +1 more source
A Constitution for the Anthropocene Body Politic
Lagoonscapes, 2021 The following article is a slightly revised version of Serenella Iovino’s Keynote Address at the 2021 European Conference for the Humanities, jointly organised in Lisbon (5-7 May) by the UNESCO Social and Human Sciences Programme, the International ...
Iovino, Serenella
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Consensus Study on the State of the Humanities in South Africa: Status, Prospects and Strategies [PDF]
, 2011 Cite: Academy of Science of South Africa (ASSAf), (2011). Consensus Study on the State of the Humanities in South Africa: Status, Prospects and Strategies. [Online] Available at: DOI http://dx.doi.org/10.17159/assaf.2016/0025The purpose of this study was
Academy of Science of South Africa (ASSAf)
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
«La penna l’ho lasciata a casa»: Letteratura e potere
Between, 2015 The current situation of the humanities, which have been resized both in university and in secondary education, seems to many the sign of a crisis that involves the role of literary knowledge, its social authority, the education of students and the ...
Cristina Nesi
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source