Results 61 to 70 of about 58,732 (256)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Adjustment of medical standards in disaster, crises and war: a scoping review of the literature

BMJ Public Health
Introduction Currently, there is a lack of evidence on how societies and healthcare systems cope with disrupting situations like disasters, crisis and wars.
Patrick Meybohm, Stephanie Weibel, Thomas Erik Wurmb, Janno Schade, Stephanie-Julia Schräder, Maximilian Kippnich   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The world health organization collaborating center for emergency and trauma (WHO-CCET) in South East Asia, the world academic council of emergency medicine (WACEM), and The American college of academic international medicine (ACAIM) 2021 framework for using telemedicine technology at healthcare institutions

Journal of Emergencies, Trauma and Shock, 2021
The coronavirus disease 2019 crisis has forced the world to integrate telemedicine into health delivery systems in an unprecedented way. To deliver essential care, lawmakers, physicians, patients, payers, and health systems have all adopted telemedicine ...
Veronica Sikka, Salvatore Di Somma, Sagar C Galwankar, Sagar Sinha, Nidhi Garg, Neilesh Talwalkar, Sona Garg, Prashant Mahajan, Vivek Chauhan, Lisa Moreno-Walton, Siddharth Dubhashi, Vibha Dutta, Venkataramanaiah Saddikuti, Prabath W B. Nanayakkara, Joydeep Grover, Ketan Paranjape, Sarman Singh, Pushpa Sharma1, Sanjeev Bhoi, Tejprakash Sinha, Stanislaw P Stawicki, Manish Garg, Indrani Sardesai   +22 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Arizona’s Crisis Standards of Care and Fair Allocation of Resources During COVID-19

, 2020
As COVID-19 cases spiked in Arizona, the state activated its crisis standards of care, which provide triage guidelines if absolute scarcity arises. Arizona has done the right thing by adopting crisis standards of care instead of leaving these decisions ...
Persad, Govind C.
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Implementation of a Pediatric Mass Casualty Triage Plan during Crisis Standards of Care Deployment

, 2014
Implementation of a Pediatric Mass Casualty Triage Plan during Crisis Standards of Care ...
Christine Gall (3813913)
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source