Results 1 to 10 of about 171,216,168 (330)

Adjunctive therapies added to standard of care for diabetic foot ulcers: a systematic review and network meta-analysis with pairwise comparisons [PDF]

Frontiers in Endocrinology
BackgroundDiabetic foot ulcers (DFUs) remain one of the most disabling and costly complications of diabetes. Although standard of care (SOC) is the foundation of DFU management, many ulcers fail to heal adequately, prompting increasing use of adjunctive ...
Wenquan Luo, Ye Sun, Yujie Weng, Kai Huang, Yu Gan   +4 more
doaj   +2 more sources

Lisocabtagene maraleucel versus standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients with relapsed or refractory large B-cell lymphoma (TRANSFORM): results from an interim analysis of an open-label, randomised, phase 3 trial

The Lancet, 2022
BACKGROUND Patients with large B-cell lymphoma (LBCL) primary refractory to or relapsed within 12 months of first-line therapy are at high risk for poor outcomes with current standard of care, platinum-based salvage immunochemotherapy and autologous ...
M. Kamdar, S. Solomon, J. Arnason, P. Johnston, B. Glass, V. Bachanova, S. Ibrahimi, S. Mielke, P. Mutsaers, F. Hernandez-Ilizaliturri, K. Izutsu, F. Morschhauser, Matthew A. Lunning, D. Maloney, A. Crotta, S. Montheard, A. Previtali, Lara Stepan, K. Ogasawara, Timothy R. Mack, J. Abramson   +20 more
semanticscholar   +1 more source

Encorafenib Plus Cetuximab as a New Standard of Care for Previously Treated BRAF V600E–Mutant Metastatic Colorectal Cancer: Updated Survival Results and Subgroup Analyses from the BEACON Study

Journal of Clinical Oncology, 2021
PURPOSE BEACON CRC evaluated encorafenib plus cetuximab with or without binimetinib versus investigators' choice of irinotecan or FOLFIRI plus cetuximab in patients with BRAFV600E–mutant metastatic colorectal cancer (mCRC), after progression on 1-2 prior
J. Tabernero, A. Grothey, E. Van Cutsem, R. Yaeger, H. Wasan, T. Yoshino, J. Desai, F. Ciardiello, F. Loupakis, Y. Hong, N. Steeghs, T. Guren, H. Arkenau, P. García-Alfonso, E. Élez, A. Gollerkeri, K. Maharry, J. Christy-Bittel, S. Kopetz   +18 more
semanticscholar   +1 more source

Brexucabtagene Autoleucel for Relapsed or Refractory Mantle Cell Lymphoma in Standard-of-Care Practice: Results From the US Lymphoma CAR T Consortium

Journal of Clinical Oncology, 2023
PURPOSE Brexucabtagene autoleucel (brexu-cel) is an autologous CD19-directed chimeric antigen receptor (CAR) T-cell therapy approved for relapsed/refractory mantle cell lymphoma (MCL).
Yucai Wang, P. Jain, F. Locke, M. Maurer, M. Frank, J. Munoz, S. Dahiya, A. Beitinjaneh, Miriam T. Jacobs, Jospeh P. McGuirk, J. Vose, A. Goy, C. Andreadis, B. Hill, K. Dorritie, Olalekan O. Oluwole, A. Deol, J. Paludo, B. Shah, T. Wang, R. Banerjee, D. Miklos, A. Rapoport, L. Lekakis, A. Ghobadi, S. Neelapu, Yi-Chung Lin, Michael L. Wang, M. Jain   +28 more
semanticscholar   +1 more source

Missed nursing care, the related organizational factors, and strategies for decreasing it from the viewpoints of nurses in university-affiliated hospitals of Birjand in 2019-2020

Iranian Journal of Nursing and Midwifery Research, 2023
Background: For many reasons, some care services may be missed. This study was conducted to investigate missed care, the related factors, and solution for decreasing them.
Seyed Hasan Ghorbani, Hadi Ahmadi Chenari, Elnaz Yazdanparast, Zohreh Javanmard, Malihe Davoudi   +4 more
doaj   +1 more source

Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial

The Lancet, 2022
Summary Background Low-grade serous carcinoma of the ovary or peritoneum is characterised by MAPK pathway aberrations and its reduced sensitivity to chemotherapy relative to high-grade serous carcinoma.
D. Gershenson, A. Miller, W. Brady, J. Paul, K. Carty, W. Rodgers, D. Millan, R. Coleman, K. Moore, Susana Banerjee, K. Connolly, A. Secord, D. O'Malley, O. Dorigo, S. Gaillard, H. Gabra, B. Slomovitz, P. Hanjani, J. Farley, M. Churchman, Ailith Ewing, Robert L. Hollis, C. Herrington, Helen Q. Huang, L. Wenzel, C. Gourley   +25 more
semanticscholar   +1 more source

Phase II Randomized Study of Ramucirumab and Pembrolizumab Versus Standard of Care in Advanced Non–Small-Cell Lung Cancer Previously Treated With Immunotherapy—Lung-MAP S1800A

Journal of Clinical Oncology, 2022
PURPOSE Resistance to immune checkpoint inhibition (ICI) in advanced non–small-cell lung cancer (NSCLC) represents a major unmet need. Combining ICI with vascular endothelial growth factor (VEGF)/VEGF receptor inhibition has yielded promising results in ...
K. Reckamp, M. Redman, K. Dragnev, K. Minichiello, Liza C. Villaruz, B. Faller, T. Albaghdadi, Susan J. Hines, Leah Everhart, Louise Highleyman, V. Papadimitrakopoulou, D. Gandara, K. Kelly, R. Herbst   +13 more
semanticscholar   +1 more source

Drug–Drug Interactions of Cannabidiol with Standard-of-Care Chemotherapeutics

International Journal of Molecular Sciences, 2023
Cannabidiol (CBD) is an easily accessible and affordable Marijuana (Cannabis sativa L.) plant derivative with an extensive history of medical use spanning thousands of years.
Tereza Buchtová, Dávid Lukáč, Zdenek Skrott, Katarína Chromá, J. Bartek, M. Mistrik   +5 more
semanticscholar   +1 more source

Patient experience with chronic obstructive pulmonary disease: a nationally representative demonstration study on quality and cost of healthcare services

Frontiers in Public Health, 2023
IntroductionDue to insufficient data on patient experience with healthcare system among patients with chronic obstructive pulmonary disease (COPD), particularly in developing countries, this study attempted to investigate the journey of patients with ...
Seyyed-Hadi Ghamari, Farnam Mohebi, Mohsen Abbasi-Kangevari, Soheil Peiman, Besharat Rahimi, Naser Ahmadi, Yousef Farzi, Shahedeh Seyfi, Nazila Shahbal, Mitra Modirian, Mehrdad Azmin, Hossein Zokaei, Maryam Khezrian, Roya Sherafat, Mohammad-Reza Malekpour, Shahin Roshani, Negar Rezaei, Negar Rezaei, Mohammad Javad Fallahi, Mohammad Javad Fallahi, Maryam Haddadzadeh Shoushtari, Zahra Akbaripour, Shahab Khatibzadeh, Saeid Shahraz   +23 more
doaj   +1 more source

Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial

Lancet. Infectious Diseases (Print), 2021
Background The antiviral efficacy of remdesivir against SARS-CoV-2 is still controversial. We aimed to evaluate the clinical efficacy of remdesivir plus standard of care compared with standard of care alone in patients admitted to hospital with COVID-19,
F. Ader, M. Bouscambert-Duchamp, M. Hites, N. Peiffer-Smadja, J. Poissy, D. Belhadi, A. Diallo, M. Lê, Gilles Peytavin, T. Staub, R. Greil, Jérémie Guedj, José-Artur Paiva, D. Costagliola, Y. Yazdanpanah, C. Burdet, F. Mentré, A. Egle, M. Joannidis, B. Lamprecht, A. Altdorfer, L. Belkhir, V. Fraipont, Gil Verschelden, J. Aboab, H. Ait-Oufella, C. Andrejak, P. Andreu, L. Argaud, F. Bani-Sadr, F. Bénézit, M. Blot, E. Botelho-Nevers, L. Bouadma, O. Bouchaud, D. Bougon, K. Bouiller, Fanny Bounes-Vardon, D. Boutoille, A. Boyer, C. Bruel, A. Cabié, E. Canet, C. Cazanave, C. Chabartier, C. Chirouze, R. Clere-Jehl, J. Courjon, F. Crockett, F. Danion, A. Delbove, J. Dellamonica, F. Djossou, C. Dubost, A. Duvignaud, O. Epaulard, L. Epelboin, M. Fartoukh, K. Faure, E. Faure, T. Ferry, C. Ficko, S. Figueiredo, B. Gaborit, Rostane Gaci, A. Gagneux-Brunon, S. Gallien, D. Garot, G. Geri, S. Gibot, F. Goehringer, M. Gousseff, D. Gruson, Y. Hansmann, O. Hinschberger, S. Jauréguiberry, Vanessa Jeanmichel, S. Kernéis, A. Kimmoun, K. Klouche, M. Lachâtre, K. Lacombe, F. Lainé, J. Lanoix, O. Launay, B. Laviolle, V. Le Moing, J. Le Pavec, Y. le Tulzo, P. Le Turnier, D. Lebeaux, B. Lefèvre, S. Leroy, F. Lescure, H. Lessire, B. Leveau, P. Loubet, A. Makinson, D. Malvy, C. Marquette, G. Martin-Blondel, M. Martinot, J. Mayaux, A. Mekontso-Dessap, F. Meziani, J. Mira, J. Molina, X. Monnet, J. Mootien, B. Mourvillier, M. Murris-Espin, J. Navellou, S. Nseir, W. Oulehri, T. Perpoint, G. Pialoux, B. Pilmis, V. Piriou, L. Piroth, V. Pourcher, J. Quenot, F. Raffi, J. Reignier, M. Revest, J. Richard, B. Riu-Poulenc, C. Robert, Pierre-Alexandre Roger, C. Roger, Elisabeth Rouveix-Nordon, Y. Ruch, N. Saidani, N. Sayre, É. Senneville, A. Sotto, François Stefan, C. Tacquard, N. Terzi, J. Textoris, G. Thiéry, J. Timsit, V. Tolsma, J. Turmel, F. Valour, F. Wallet, Guilhem Wattecamps, Y. Zerbib, M. Berna, J. Reuter, S. Braz, Joao-Miguel Ferreira Ribeiro, José-Artur Paiva, R. Roncon-Albuquerque, A. Gaymard, B. Lina, S. Tubiana, S. Couffin-cadiergues, H. Esperou, Aline Dechanet, C. Delmas, C. Fougerou, N. Mercier, M. Noret, J. Saillard, Priyanka Velou   +164 more
semanticscholar   +1 more source