Results 121 to 130 of about 54,706 (289)
Genotyping with CRISPR-Cas-derived RNA-guided endonucleases [PDF]
, 2014 Jong Min Kim +3 more
openalex +1 more source
CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnostics [PDF]
, 2021 Liangliang Hao +5 more
openalex +1 more source
, 2016 Bacteria can receive genetic material from other bacteria or invading bacteriophages primarily through horizontal gene transfer. These genetic exchanges can result in genome rearrangement and the acquisition of novel traits that assist cells with stresses and adverse environmental conditions.
Hakim, Joseph A. +4 more
openaire +1 more source
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
Advanced Science, EarlyView.Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu +13 more
wiley +1 more source
Comprehensive Analysis of CRISPR-Cas Systems and Their Influence on Antibiotic Resistance in Strains
Bioinformatics and Biology InsightsSalmonella enterica is a gram-negative bacterium that demonstrates a remarkable ability to acquire antibiotic resistance genes (ARGs). The role of the CRISPR-Cas system in influencing antibiotic resistance in S.
Tina Fallah, Morvarid Shafiei
doaj +1 more source
CRISPR-Cas-Based Engineering of Probiotics
, 2023 Ling Liu, Shimaa Elsayed Helal, Nan Peng
openalex +1 more source
Advanced Science, EarlyView.Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen +14 more
wiley +1 more source
CcpA and CodY Regulate CRISPR-Cas System of Streptococcus mutans
, 2023 Dayoung Kang, Andy Kim, Jeong Nam Kim
openalex +1 more source
ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
Advanced Science, EarlyView.ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song +12 more
wiley +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source