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Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
Nature Biotechnology, 2020Andrew V. Anzalone +2 more
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Nature Reviews Molecular Cell Biology, 2019
CRISPR–Cas9-based prime editing supports the correction of a wide range of mutations, including transversions and insertions and deletions.
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CRISPR–Cas9-based prime editing supports the correction of a wide range of mutations, including transversions and insertions and deletions.
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2013
Discovery and seminal developments in the CRISPR field.- Occurrence, diversity of CRISPR-Cas systems and genotyping implications.- Evolution and classification of CRISPR-Cas systems and Cas protein families.- Regulation of CRISPR-based immune responses.- crRNA Biogenesis.- Distribution and mechanism of the Type I CRISPR/Cas Systems.- Type II ...
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Discovery and seminal developments in the CRISPR field.- Occurrence, diversity of CRISPR-Cas systems and genotyping implications.- Evolution and classification of CRISPR-Cas systems and Cas protein families.- Regulation of CRISPR-based immune responses.- crRNA Biogenesis.- Distribution and mechanism of the Type I CRISPR/Cas Systems.- Type II ...
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2021
The Nobel Prize in Chemistry in 2020 was awarded to two researchers in the field of molecular biology: French Emmanuelle Charpentier, who currently heads the Max Planck Unit for the Science of Pathogens (Berlin, Germany), and American Jennifer Doudna of the University of California (Berkeley, CA, USA) ???for the development of a method for genome ...
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The Nobel Prize in Chemistry in 2020 was awarded to two researchers in the field of molecular biology: French Emmanuelle Charpentier, who currently heads the Max Planck Unit for the Science of Pathogens (Berlin, Germany), and American Jennifer Doudna of the University of California (Berkeley, CA, USA) ???for the development of a method for genome ...
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Crowd-sourced CRISPR-Cas responses
Science, 2016Microbiology Bacterial populations can coordinate their responses to environmental change by quorum sensing. Bacteria also possess protective combinations of clustered regularly interspaced short palindromic repeats and associated proteins (CRISPR-Cas) to defend themselves against viral predation and attack by mobile elements. Patterson et al.
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CRISPR/Cas, the Immune System of Bacteria and Archaea
Science, 2010P. Horvath, R. Barrangou
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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Nature, 2010Josiane E. Garneau +9 more
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Targeted genome modification of crop plants using a CRISPR-Cas system
Nature Biotechnology, 2013Qi-wei Shan +10 more
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