Results 271 to 280 of about 713,183 (311)
Competition between mobile genetic elements drives optimization of a phage-encoded CRISPR-Cas system: Insights from a natural arms-race [PDF]
, 2018 Amelia C. McKitterick +4 more
openalex +1 more source
Animal Research and One Health, EarlyView.This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah +4 more
wiley +1 more source
The search and analysis of a CRISPR-Cas system in Escherichia coli HS with subsequent scanning for the corresponding phage races based on the spacers of the detected CRIPSR array using bioinformatic methods [PDF]
, 2018 Е. И. Иванова +9 more
openalex +1 more source
Autism Research, EarlyView.ABSTRACT Among autistic individuals, a subphenotype of disproportionate megalencephaly (ASD‐DM) seen at three years of age is associated with co‐occurring intellectual disability and poorer prognoses later in life. However, many of the genes contributing to ASD‐DM have yet to be delineated. In this study, we identified additional ASD‐DM candidate genes
Sierra S. Nishizaki +10 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Unspecific peroxygenases (UPOs) and cytochrome P450 monooxygenases (CYPs) with peroxygenase activity are becoming the preferred biocatalysts for oxyfunctionalization reactions. While whole cells (WCs) or cell‐free extracts (CFEs) of Escherichia coli are often preferred for cofactor‐dependent monooxygenase reactions, hydrogen peroxide (H2O2 ...
Ana C. Ebrecht +5 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Escherichia coli accumulates acetate as a byproduct in fast growth aerobic conditions when using glucose as carbon source. This phenomenon, known as overflow metabolism, has negative impacts on cell growth and protein expression, also causes carbon loss during biosynthesis in most microbial production scenarios. In this study, we regarded the “
Jianli Zhang +8 more
wiley +1 more source
Industrial Dynamics and Business Strategies in the Emergence of Agricultural Biological Inputs
Business Strategy and the Environment, EarlyView.ABSTRACT Biological products present a sustainable alternative to synthetic agricultural inputs, yet the industrial dynamics triggered by these solutions remain unexplored. This study examines the strategic responses of dominant agricultural input firms to the rise of biological solutions. Through qualitative textual analysis of press releases, company
Pablo Mac Clay +3 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract We present the first use of a bioengineered mammalian transposase system derived from Myotis lucifugus (bMLT) for integration of expression vectors into the CHO genome, focusing on GFP and trastuzumab production. Initially, CHO‐K1 cells are transfected with a GFP reporter and varying amounts of bMLT DNA or mRNA.
Nicolas Marx +10 more
wiley +1 more source
Classification and Nomenclature of CRISPR-Cas Systems: Where from Here?
, 2018 Kira S. Makarova +2 more
openalex +1 more source
Breaking barriers: Smart vaccine platforms for cancer immunomodulation
Cancer Communications, EarlyView.Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari +11 more
wiley +1 more source