Results 261 to 270 of about 333,510 (359)

The rapid detection of human HLA-B*27 gene based on BASIC isothermal detection. [PDF]

Sci Rep
Chen Y, Ren J, Yang X, Li Z, Wu W, Luo G, Xu Y, Yang H, Wang Q, Zhang Q.   +9 more
europepmc   +1 more source

Persisting Viral Sequences Shape Microbial CRISPR-based Immunity

, 2012
Ariel D. Weinberger, Christine Sun, Mateusz M. Pluciński, Vincent J. Denef, Brian C. Thomas, Philippe Horvath, Rodolphe Barrangou, Michael S. Gilmore, Wayne M. Getz, Jillian F. Banfield   +9 more
openalex   +2 more sources

Efficient genome editing in Caenorhabditis elegans by CRISPR-targeted homologous recombination [PDF]

, 2013
Changchun Chen, Lorenz A. Fenk, Mario de Bono   +2 more
openalex   +1 more source

ISG15 Enhances the Activity of γ‐Glutamate Cysteine Ligase to Suppress Apoptosis in High Fat Diet‐Promoted Hepatocellular Carcinoma

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC) cells under high‐fat environment constrain harmful reactive oxygen species (ROS) by enhancing glutathione synthesis though upregulating interferon stimulated gene 15 (ISG15). In this process, upregulated high mobility group A1 (HMGA1) enhances ISG15 transcription, upregulated ISG15 subsequently noncovalently binds with ...
Xinran Liu, Qiujin Ma, Zhao Jia, Yihao Zhou, Churong Zou, Yushuo Xiao, Yuchen Chen, Chuyao Ma, Liangliang Song, Jing Yang, Chen Wang, Huidie Xu, Hong Chen, Jiajian Shi, Junqiu Yue, Yu Sun, Desheng Hu, Robert B Petersen, Yangkai Li, Anlin Peng, Kun Huang, Ling Zheng   +21 more
wiley   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

CRISPR/Cas9-Based therapeutics as a promising strategy for management of Alzheimer's disease: progress and prospects. [PDF]

Front Cell Neurosci
Khan MS, Qureshi N, Khan R, Son YO, Maqbool T.   +4 more
europepmc   +1 more source

Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes [PDF]

, 2013
Daisuke Mashiko, Samantha A. M. Young, Masanaga Muto, Hirotaka Kato, Kaori Nozawa, Masaki Ogawa, Taichi Noda, Yeon‐Joo Kim, Yuhkoh Satouh, Yoshitaka Fujihara, Masahito Ikawa   +10 more
openalex   +1 more source

Nanoparticle Delivery of Antisense miR162 Inhibits Invasive Habitat Adaption of Alternanthera Philoxeroides

Advanced Science, EarlyView.
This study demonstrates that the miRNA pathway plays a key role in the invasive growth of Alternanthera philoxeroides in aquatic habitats. Specifically, miR162 is critical for its invasive success, facilitating stem elongation and enhancing survival during submergence.
Qianqian Hu, Erfeng Kou, Xiuzhen Liao, Ruiyi Qiu, Qi Tang, Huan Zhang, Yun Zheng, Ji Yang, Binglian Zheng   +8 more
wiley   +1 more source

Rapid and visual detection of transmissible gastroenteritis virus using a CRISPR/Cas12a system combined with loop-mediated isothermal amplification. [PDF]

BMC Vet Res
Wang H, Qi Z, Wang J, He Z, Lu L, Chen Z, Shao Y, Wang G, Wang Z, Tu J, Song X.   +10 more
europepmc   +1 more source

Active site plasticity enables metal-dependent tuning of Cas5d nuclease activity in CRISPR-Cas type I-C system [PDF]

, 2013
Ankita Punetha, Raveendran Sivathanu, Baskaran Anand   +2 more
openalex   +1 more source