Results 91 to 100 of about 993,287 (302)

The operationalized psychodynamic diagnostics system. Clinical relevance, reliability and validity [PDF]

, 2007
In this paper, we present a multiaxial system for psychodynamic diagnosis, which has attained wide usage in Germany in the last 10 years. First we will discuss the 4 operationalized psychodynamic diagnostics (OPD) axes: illness experience and treatment ...
Bellak L, Benjamin LS, Cierpka M, Crits-Christoph P, Fleiss JL, Foa UG, G. Rudolf, Gill MM, Grande T, Grunberger U, M. Cierpka, M. Stasch, M. von der Tann, Michels R, Perry JC, Perry JC, Pilkonis PA, Rudolf G, Rudolf G, Schneider G, Stasch M, Stiles WB, Strauss B, T. Grande, Wallerstein RS, Weinryb RM   +25 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Examining the factor structure of the teachers’ sense of efficacy scale - short form in a Serbian sample of elementary-level teachers: A bifactor-ESEM approach [PDF]

Psihologija
This study explored the factor structure of the short form of the Teachers’ Sense of Efficacy Scale (TSES-Sf) using Confirmatory Factor Analysis (CFA), and Exploratory Structural Equation Modeling (ESEM), as well as bifactor models based on these two ...
Lazić Milica, Marić-Jurišin Stanislava, Malčić Borka   +2 more
doaj   +1 more source

On the Physics of the Riemann Zeros [PDF]

, 2010
We discuss a formal derivation of an integral expression for the Li coefficients associated with the Riemann xi-function which, in particular, indicates that their positivity criterion is obeyed, whereby entailing the criticality of the non-trivial zeros.
He, Yang-Hui, Jejjala, Vishnu, Minic, Djordje   +2 more
core   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

The criterion validity of the web-based Major Depression Inventory when used on clinical suspicion of depression in primary care

Clinical Epidemiology, 2017
Marie Germund Nielsen,1 Eva Ørnbøl,2 Per Bech,3 Mogens Vestergaard,1,4 Kaj Sparle Christensen1 1Research Unit for General Practice, Department of Public Health, Aarhus University, 2Research Clinic for Functional Disorders and Psychosomatics,
Nielsen MG, Ørnbøl E, Bech P, Vestergaard M, Christensen KS   +4 more
doaj  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Validation of the PILL-5: A 5-Item Patient Reported Outcome Measure for Pill Dysphagia. [PDF]

, 2019
Objectives: Pill dysphagia is common and costly with a significant risk of pill retention, caustic injury, and poor medication compliance. The purpose of this investigation was to determine the validity and reliability of the PILL-5, a self-administered ...
Bayoumi, Ahmed, Belafsky, Peter C, Kaufman, Matthew, Kuhn, Maggie A, Mandin, Van Pierre, Nativ-Zeltzer, Nogah, Seeni, Indulaxmi   +6 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A New Criterion for Clusters Validation [PDF]

, 2011
In this paper a new criterion for clusters validation is proposed. This new cluster validation criterion is used to approximate the goodness of a cluster. The clusters which satisfy a threshold of this measure are selected to participate in clustering ensemble.
Alizadeh, Hosein, Minaei, Behrouz, Parvin, Hamid   +2 more
openaire   +2 more sources