Results 71 to 80 of about 216,591 (259)

The Concurrent Validity and Test–Retest Reliability of a Smartphone-Based Markerless System

open access: yesSensors
Increasing the accessibility and portability of precise biomechanical data to sports scientists can assist in making data-driven decisions. The purpose of this study was: (1) Assess the concurrent and convergence validity of discrete and continuous ...
Kristen F. Nicholson   +6 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Avaliação do funcionamento cognitivo por meio do CAT-A: evidências de validade Cognitive assessment using the CAT-A: validity evidence

open access: yesPsicologia: Reflexão e Crítica, 2013
O objetivo desse estudo foi trazer evidências de validade do CAT-A para avaliação do funcionamento cognitivo em crianças. Correlacionou-se indicadores cognitivos no CAT-A; DFH e Rorschach no Sistema Compreensivo. Inicialmente, com base no DFH, selecionou-
Maria de Fátima Xavier   +1 more
doaj  

Reliability, Criterion Validity, and Agreement of the Global Physical Activity Questionnaire Against Accelerometry Among High-Risk Individuals for Type 2 Diabetes in India

open access: yesDiabetology
Objectives: We assessed the test–retest reliability, criterion validity, and agreement of the Global Physical Activity Questionnaire (GPAQ) against accelerometry for estimating physical activity (PA) and sedentary behaviour (SB) among Indian adults at ...
Sathish Thirunavukkarasu   +8 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Accommodating flourishing and depressive symptoms into the bifactor (S–1) model of mental health: longitudinal invariance and criterion validity

open access: yesFrontiers in Psychology
This study examined the longitudinal reliability and validity of the bifactor (S–1) model of mental health among 371 Chinese university students, refining the dual-factor model that views mental health as encompassing both flourishing and ...
Chaoran Sun, Sylvia Kwok, Yu Huang
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Reliability and Diagnostic Accuracy of Commonly Used Performance Tests Relative to Fall History in Older Persons: A Systematic Review

open access: yesClinical Interventions in Aging, 2021
Simone Chantal Gafner,1,2 Lara Allet,3,4 Roger Hilfiker,4 Caroline Henrice Germaine Bastiaenen2 1Geneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland, Geneva, Switzerland; 2Department of Epidemiology ...
Gafner SC   +3 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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