Results 41 to 50 of about 19,175 (267)

The Deleuzian reappropriation of Hume and the transformation of the problem of knowledge

Eikasía
This paper aims to offer a reconstruction of the way Gilles Deleuze treated the problem of knowledge in the study which initiated the phase of a history of philosophy: Empiricism and subjectivity. We will try to show that whereas Deleuze subordinates the
Gabriel Martín Torres, Javier Roque Alegre   +1 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comment construit-on l’histoire de la géographie ?

Terra Brasilis, 2013
To get to understand geography’s past, it would be convenient to pass from the spontaneous memorization, generally oral, to an organized approach. Despite the precautions taken during its elaboration, ‘scientific’ history carries the mark of the concerns
Paul Claval
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Reflexiones sobre la Lectura Crítica desde una Perspectiva Freireana en la Educación Básica

Revista Brasileira de Pesquisa em Educação em Ciências, 2022
En este estudio proponemos abordar la lectura crítica de textos de prensa con contenido científico apoyados en la perspectiva freireana y en el CRITIC — desarrollado por Bartz (2002) y adaptado por Oliveras et al. (2013).
Dayana do Nascimento Ferreira, Andrea Revel Chion, Márcia Gorette Lima da Silva   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Les approches sociotechniques dans la sociologie des usages en SIC

Revue Française des Sciences de l’Information et de la Communication, 2015
Studies relying on a sociotechnical approach are often quoted, especially since the success of the innovation sociology center works in France. Nevertheless, these are only one kind of sociotechnical approach while several research current are relying on
Alexandre Coutant
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source