Results 61 to 70 of about 19,175 (267)
PİSAGOR BULANIK SAYILARA DAYALI CRITIC-MARCOS YÖNTEMİ İLE OTONOM FORKLİFT SEÇİMİ
Eskişehir Osmangazi Üniversitesi Mühendislik ve Mimarlık Fakültesi DergisiÜretim ve depolama işletmelerinde forkliftler işletmenin verimliliğini arttırmak amacıyla yaygın olarak kullanılmaktadır. Özellikle son yıllarda teknolojide yaşanan gelişmeler ve Endüstri 4.0 uygulamaları ile otonom forkliftler modern işletmelerde klasik
Elif Çaloğlu Büyükselçuk
doaj +1 more source
ReS Futurae, 2013 Dans cet entretien, Ugo Bellagamba et Éric Picholle présentent les enjeux théoriques des Journées Science et Fiction de Peyresq, consacrées chaque année à des réflexions sur les rapports entre la science-fiction et les différents champs du savoir.
Ugo Bellagamba +3 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Aportes de la entrevista clínica-crítica al campo de las Ciencias Sociales
EMPIRIA: Revista de Metodología de Ciencias SocialesEl presente artículo tiene como objetivo principal hacer observable el enorme potencial analítico de un método insuficientemente explorado y/o explotado por las ciencias sociales: el método clínico crítico, desarrollado por Jean Piaget en sus ...
Edna Analía Muleras +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Актуальні питання суспільних наук та історії медицини, 2019 вороном”. Цель работы: определение места научной доработ- ки Ю. Стефаника в украинском литературоведении, выяснение значения его вклада в осмыслении литературного про- цесса в Украине в ХХ столетии, обобщение научных поисков в исследовании жизни и ...
Антоній МОЙСЕЙ +1 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source