Results 31 to 40 of about 4,960,171 (291)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Calcium modeling of spine apparatus-containing human dendritic spines demonstrates an "all-or-nothing" communication switch between the spine head and dendrite.

open access: yesPLoS Computational Biology, 2022
Dendritic spines are highly dynamic neuronal compartments that control the synaptic transmission between neurons. Spines form ultrastructural units, coupling synaptic contact sites to the dendritic shaft and often harbor a spine apparatus organelle ...
James Rosado   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Navigating Deposited Subjectivities

open access: yesKrisis
Review of Greg Bird and Giovanbattista Tusa (eds). 2023. Dispositif: A Cartography. MIT Press.  This is a review of Dispositif: A Cartography. It presents an effort to use the book as was perhaps intended, to navigate a particular set of dispositives ...
Arthur Willemse
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A comparative study between the NGI direct simple shear apparatus and the Mikasa direct shear apparatus [PDF]

open access: yes, 2007
A comparative study of the NGI Direct Simple Shear Test (DSST) and the Mikasa Direct Shear Test (DST) is reported. Samples from Norwegian Drammen clay and Japanese Ariake clay were subjected to both types of test.
Hanzawa, Hideo   +9 more
core   +1 more source

Drag Reduction Study of Xathan Gum with Polydiallyldimethylammonium Chloride (PDDAC) Solutions in Turbulent Flow [PDF]

open access: yesEngineering and Technology Journal, 2018
The transportation of liquids through pipelines is attributed with high-energy consumption due to the turbulent nature of their transportation. Low concentrations of polymeric additives were proven effective flow enhancing agent when injected into these ...
Zainab Yousif
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The Politics of Film: 'Captain Volkonogov Escaped' and the Art of Resistance [PDF]

open access: yes, 2023
Natasha Merkulova and Aleksey Chupov's Captain Volkonogov Escaped offers a gripping portrayal of life in Stalin's Soviet Union. This article discusses the film's evocation of an oppressive social structure and its pertinence as a stimulus and means to ...
Robinson, P. Stuart
core   +1 more source

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