Results 1 to 10 of about 5,205,884 (314)

Quality Improvement in Critical Care: Selection and Development of Quality Indicators

Canadian Respiratory Journal, 2016
Background. Caring for critically ill patients is complex and resource intensive. An approach to monitor and compare the function of different intensive care units (ICUs) is needed to optimize outcomes for patients and the health system as a whole ...
Carla A. Chrusch, Claudio M. Martin, The Quality Improvement in Critical Care Project   +2 more
doaj   +1 more source

Mesenchymal Stem Cell-Secreted TGF-β1 Restores Treg/Th17 Skewing Induced by Lipopolysaccharide and Hypoxia Challenge via miR-155 Suppression

Stem Cells International, 2022
Background. Regulatory T cell (Treg)/T helper (Th) 17 skewing is important in the development of acute respiratory distress syndrome (ARDS). Immunomodulatory effects of mesenchymal stem cell- (MSC-) secreted transforming growth factor- (TGF-) β1 on CD4 ...
Ming Xue, Xiwen Zhang, Jianxiao Chen, Feng Liu, Jingyuan Xu, Jianfeng Xie, Yi Yang, Weiping Yu, Haibo Qiu   +8 more
doaj   +1 more source

Relationship between Nonhepatic Serum Ammonia Levels and Sepsis-Associated Encephalopathy: A Retrospective Cohort Study

Emergency Medicine International, 2023
Objectives. Nonhepatic hyperammonemia often occurs in patients with sepsis. Ammonia plays an essential role in the occurrence of hepatic encephalopathy.
Pei Wang, Jia Yan, Qiqing Shi, Fei Yang, Xuguang Li, Yuehao Shen, Haiying Liu, Keliang Xie, Lina Zhao   +8 more
doaj   +1 more source

The Neutrophil-to-Lymphocyte Ratio is Associated with the Requirement and the Duration of Invasive Mechanical Ventilation in Acute Respiratory Distress Syndrome Patients: A Retrospective Study

Canadian Respiratory Journal, 2022
Background. Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality and most ARDS patients require ventilatory support.
Lijuan Yang, Chang Gao, Ying He, Xiaowan Wang, Ling Yang, Shiqi Guo, Jiahao Chen, Siyu He, Yuanxiao Sun, Ye Gao, Qiang Guo   +10 more
doaj   +1 more source

Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p

Journal of Immunology Research, 2023
Background. Sepsis-induced acute lung injury is a common critical illness in intensive care units with no effective treatment is currently available.
Wei Peng, Yun Yang, Jiaquan Chen, Zeyao Xu, Yuanlei Lou, Qi Li, Ning Zhao, Kejian Qian, Fen Liu   +8 more
doaj   +1 more source

Understanding Causes of Death in Patients With Acute Respiratory Distress Syndrome: A Narrative Review

Critical Care Explorations
OBJECTIVES:. To provide a comprehensive summary of the published data on cause of death in patients with acute respiratory distress syndrome (ARDS). DATA SOURCES:. PubMed (January 2015 to April 2024), bibliographies of relevant articles, and ARDS Network
Susan E. Bromley, MSc, Kaweh Shakery, MD, Pareen Vora, PhD, Artin Atabaki, PhD, Thomas Reimer, MD, Fellowship in Critical Care, Lawrence McDermott, MD, Fellowships in Pulmonary and Critical Care, Negin Hajizadeh, MD, Fellowships in Medical Informatics, Pulmonary and Critical Care   +6 more
doaj   +1 more source

Severe heat stroke complicated by multiple cerebral infarctions: a case report

Journal of Medical Case Reports, 2021
Background Heat-related illnesses include symptoms such as heat syncope/cramps, heat exhaustion, and life-threatening heat stroke. Usually, a heat stroke causes cerebellar ataxia, cognitive impairment, dysphagia, and aphasia.
Ryo Kamidani, Hideshi Okada, Yuichiro Kitagawa, Keigo Kusuzawa, Masahiro Ichihashi, Yoshinori Kakino, Hideaki Oiwa, Ryu Yasuda, Tetsuya Fukuta, Naomasa Yoshiyama, Takahito Miyake, Haruka Okamoto, Kodai Suzuki, Noriaki Yamada, Tomoaki Doi, Takahiro Yoshida, Hiroaki Ushikoshi, Keisuke Kumada, Shozo Yoshida, Shinji Ogura   +19 more
doaj   +1 more source

Data-driven spatial–temporal framework for exploring the heterogeneity and temporality of sepsis

Chinese Medical Journal
. Sepsis remains a leading cause morbidity and mortality worldwide; effective targeted therapies remain elusive due to its inherent heterogeneity and dynamic temporal evolution.
Yehan Qiu, Xiang Zhou, On behalf of China Critical Care Clinical Trials Group (CCCCTG) and China National Critical Care Quality Control Center Group (China-NCCQC group), Xuehong Zhang, Jing Ni   +4 more
doaj   +1 more source

ANXA1sp Protects against Sepsis-Induced Myocardial Injury by Inhibiting Ferroptosis-Induced Cardiomyocyte Death via SIRT3-Mediated p53 Deacetylation

Mediators of Inflammation, 2023
Sepsis-induced myocardial injury (SIMI), a common complication of sepsis, may cause significant mortality. Ferroptosis, a cell death associated with oxidative stress and inflammation, has been identified to be involved in SIMI.
Song Qin, Yingcong Ren, Banghai Feng, Xiaoqin Wang, Junya Liu, Jie Zheng, Kang Li, Miao Chen, Tao Chen, Hong Mei, Xiaoyun Fu   +10 more
doaj   +1 more source

Critical care audit [PDF]

Canadian Journal of Anaesthesia, 1992
Critical care utilization in Canada increased from 17 ICU patient days per thousand population in 1969 to 42 ICU patient days per thousand population in 1986) This represented approximately 8% of 1986 total inpatient costs. In the same year, intensive care utilization in the United States was 108 patient days per thousand population, accounting for 20%
openaire   +2 more sources