Results 41 to 50 of about 10,286,525 (296)

Severe heat stroke complicated by multiple cerebral infarctions: a case report

Journal of Medical Case Reports, 2021
Background Heat-related illnesses include symptoms such as heat syncope/cramps, heat exhaustion, and life-threatening heat stroke. Usually, a heat stroke causes cerebellar ataxia, cognitive impairment, dysphagia, and aphasia.
Ryo Kamidani, Hideshi Okada, Yuichiro Kitagawa, Keigo Kusuzawa, Masahiro Ichihashi, Yoshinori Kakino, Hideaki Oiwa, Ryu Yasuda, Tetsuya Fukuta, Naomasa Yoshiyama, Takahito Miyake, Haruka Okamoto, Kodai Suzuki, Noriaki Yamada, Tomoaki Doi, Takahiro Yoshida, Hiroaki Ushikoshi, Keisuke Kumada, Shozo Yoshida, Shinji Ogura   +19 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Mesenchymal Stem Cell-Secreted TGF-β1 Restores Treg/Th17 Skewing Induced by Lipopolysaccharide and Hypoxia Challenge via miR-155 Suppression

Stem Cells International, 2022
Background. Regulatory T cell (Treg)/T helper (Th) 17 skewing is important in the development of acute respiratory distress syndrome (ARDS). Immunomodulatory effects of mesenchymal stem cell- (MSC-) secreted transforming growth factor- (TGF-) β1 on CD4 ...
Ming Xue, Xiwen Zhang, Jianxiao Chen, Feng Liu, Jingyuan Xu, Jianfeng Xie, Yi Yang, Weiping Yu, Haibo Qiu   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationship between Nonhepatic Serum Ammonia Levels and Sepsis-Associated Encephalopathy: A Retrospective Cohort Study

Emergency Medicine International, 2023
Objectives. Nonhepatic hyperammonemia often occurs in patients with sepsis. Ammonia plays an essential role in the occurrence of hepatic encephalopathy.
Pei Wang, Jia Yan, Qiqing Shi, Fei Yang, Xuguang Li, Yuehao Shen, Haiying Liu, Keliang Xie, Lina Zhao   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Frequency of clinical alarms in intensive care units and nurses’ sensitivity to them: An observational study

, 2021
Background All clinical alarms require nurses to respond even if an intervention is not needed. Nurses are expected to respond appropriately to each alarm and establish priorities among their care practices accordingly.
Ceylan, Burcu, Güneş, Ülkü Yapucu, Baran, Leyla, Güneş, Ülkü   +3 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

From critical care nephrology to critical care blood purification [PDF]

Journal of Translational Internal Medicine, 2021
Yang, Rongli, Chen, Xiukai, Li, Suwei, Wang, Xiaoting, Liu, Dawei   +4 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source