Results 51 to 60 of about 10,286,525 (296)

Relationship Between Intensive Care Unit Delirium Severity and 2-Year Mortality and Health Care Utilization [PDF]

open access: yes, 2020
Background: Critical care patients with delirium are at an increased risk of functional decline and mortality long term. Objective: To determine the relationship between delirium severity in the intensive care unit and mortality and acute health care ...
Boustani, Malaz   +7 more
core   +1 more source

Sepsis induced coagulopathy (SIC): is it monolithic?

open access: yesThrombosis Journal
Introduction Sepsis-induced coagulopathy (SIC) is known to be linked with an increased mortality of sepsis. Methods We designed this study to investigate whether there is heterogeneity in the clinical manifestations of SIC between cases with ...
Lu Wang   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

National Adult Critical Care Capacity Census and Activity Census 2016

open access: yes, 2017
he annual national adult Critical Care Bed Capacity Census measures capacity as at 30th September 2016. The Census reports a capacity of 237 adult critical care (Level3 ICU and Level2 HDU) beds.
HSE Acute Hospitals Division Critical Care Programme
core  

Association of Albumin–Bilirubin (ALBI) Grade With 28-Day All-Cause Mortality in Patients With Acute Respiratory Distress Syndrome: A Retrospective Analysis of the MIMIC-IV Database

open access: yesMediators of Inflammation
The albumin–bilirubin (ALBI) grade, a validated prognostic tool in cancers such as hepatocellular carcinoma, has not been evaluated in acute respiratory distress syndrome (ARDS).
Weixiao Chen   +7 more
doaj   +1 more source

Stress induced cardiomyopathy complicated by cardiogenic shock: A non-survivor case

open access: yesEgyptian Journal of Critical Care Medicine, 2018
Stress induced cardiomyopathy complicated by refractory cardiogenic shock is challenging as treatment by inotropes and vasopressors may be ineffective.
M. Abouelwafa   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Value of Glycemic Gap for Predicting Mortality in ICU in Patients With and Without Diabetes

open access: yesJournal of Diabetes Research
Conclusion: The glycemic GAP between the mean level of blood glucose within the first 7 days in ICU and ADAG was independently associated with 28-day mortality of critically ill patients, which was different between patients with and without diabetes ...
Ran Lou   +10 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Optimizing nutrition in intensive care units: Empowering critical care nurses to be effective agents of change

open access: yes, 2012
Observational studies have consistently revealed wide variation in nutritional practices across intensive care units and indicated that the provision of adequate nutrition to critically ill patients is suboptimal.
Cahill, Naomi E   +8 more
core   +1 more source

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