Results 101 to 110 of about 504,630 (309)

Hairy black holes and holographic heat engine

Nuclear Physics B, 2020
By considering AdS charged black hole in the context of extended thermodynamic as the working substance we use it as a heat engine. We investigate the effect of hairy charge on the evolution of efficiency and Carnot efficiency along with electric charge.
H. Ghaffarnejad, E. Yaraie, M. Farsam, K. Bamba   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Advancing State of Charge Management in Electric Vehicles With Machine Learning: A Technological Review

IEEE Access
As the share of electric vehicles increases, electric vehicles are exposed to broader of driving conditions (e.g., extreme weather), which reduce the performance and driving ranges of electric vehicles below their nameplate rating.
Arash Mousaei, Yahya Naderi, I. Safak Bayram   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Scaling dimensions of higher-charge monopoles at deconfined critical points [PDF]

, 2015
The classical cubic dimer model has a columnar ordering transition that is continuous and described by a critical Anderson–Higgs theory containing an SU(2)-symmetric complex field minimally coupled to a noncompact U(1) gauge theory.
Powell, Stephen, Sreejith, G.J., Sreejith, G., Powell, S.   +3 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Charge-carrier transport and recombination in heteroepitaxial CdTe [PDF]

, 2014
We analyze charge-carrier dynamics using time-resolved spectroscopy and varying epitaxial CdTe thickness in undoped heteroepitaxial CdTe/ZnTe/Si.
S. Farrell (4776546), P. Dippo (7940102), S. Sivananthan (7940096), D. Kuciauskas (7940099), E. Colegrove (7940093)   +4 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Experimental Study of Cycle Characteristics on CO2 Hydrate Cool Storage System

Zhileng xuebao, 2018
The characteristics of system cycle and cool storage of CO2 Hydrate with an initial charge pressure of 3.5–4.0 MPa were investigated in the direct-contact type cool storage test bench. Based on the experimental data, the p-h diagram of the cycle and cool
Zhuang Yaqi, Xie Yingming, Geng Shijiang
doaj  

A critical charge for improving opioid use disorder outcomes along the cascade. [PDF]

Am J Drug Alcohol Abuse, 2021
Williams AR.
europepmc   +1 more source