Results 91 to 100 of about 504,630 (309)

Novel equal area law and analytical charge-electric potential criticality for charged Anti-de Sitter black holes

open access: yesPhysics Letters B, 2019
We study the equal area law and charge-electric potential criticality for the charged Anti-de Sitter black holes. Considering that the black hole charge is a double-valued function of the electric potential, we investigate the equal area law in detail ...
Run Zhou, Shao-Wen Wei
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Phase transition and critical phenomena of charged Einstein–Maxwell-scalar black holes

open access: yesEuropean Physical Journal C: Particles and Fields
We study the phase transition and critical phenomenon of charged black holes in Einstein–Maxwell-scalar (EMs) theory. Through comprehensive analysis of thermodynamic behaviors manifested in $$P-V$$ P - V diagrams, G(T, P) surfaces, and $$C_P$$ C P curves,
Zeming Zhuang, Kun Meng, Hongsheng Zhang
doaj   +1 more source

Anomalous thermo-osmotic conversion performance of ionic covalent-organic-framework membranes in response to charge variations

open access: yesNature Communications, 2022
The development of ionic membranes with a high charge population is critical for realizing efficient thermo-osmotic energy conversion. Here, the authors demonstrated that the thermo-osmotic energy conversion efficiency can be improved by increasing the ...
Weipeng Xian   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Enhancing lung transplantation with ECMO: a comprehensive review of mechanisms, outcomes, and future considerations

open access: yesThe Journal of ExtraCorporeal Technology
Background: Lung transplantation (LTx) is a critical intervention for patients with end-stage lung disease. However, challenges such as donor organ scarcity and post-transplant complications significantly affect its success.
Pervaiz Butt Salman   +20 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Criticality in charge-asymmetric hard-sphere ionic fluids

open access: yesPhysical Review E, 2005
25 pages, 14 figures; last update with typos corrected and some added ...
Aqua, Jean-Noël   +2 more
openaire   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Effects of string cloud on Gauss-Bonnet holographic superconductors

open access: yesPhysics Letters B, 2019
The effects of the string cloud on higher-dimensional holographic superconductors in Einstein-Gauss-Bonnet gravity are investigated in the probe limit. The critical temperature is analytically obtained using Sturm-Liouville eigenvalue method.
Cao H. Nam
doaj   +1 more source

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