Results 91 to 100 of about 470,590 (265)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Constraints from accretion onto a Tangherlini–Reissner–Nordstrom black hole

European Physical Journal C: Particles and Fields, 2019
We investigate spherically symmetric, steady state, adiabatic accretion onto a Tangherlini–Reissner–Nordstrom black hole in arbitrary dimensions by using D-dimensional general relativity. We obtain basic equations for accretion and determine analytically
Rongjia Yang
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Charge-density-wave quantum critical point under pressure in 2H-TaSe2

Communications Physics
The presence of a quantum-critical point (QCP) at which a nearby ordered phase is suppressed to zero temperature is often invoked to explain emergent quantum phases, e.g. superconductivity.
Yuliia Tymoshenko, Amir-Abbas Haghighirad, Rolf Heid, Tom Lacmann, Alsu Ivashko, Adrian Merritt, Xingchen Shen, Michael Merz, Gaston Garbarino, Luigi Paolasini, Alexei Bosak, Florian K. Diekmann, Kai Rossnagel, Stephan Rosenkranz, Ayman H. Said, Frank Weber   +15 more
doaj   +1 more source

Charge critical sensors first: Minimize data loss in wireless rechargeable sensor networks

International Journal of Distributed Sensor Networks, 2018
In this article, we study the scheduling of a charging vehicle to replenish sensor energy in a large-scale wireless sensor network, by utilizing the novel wireless energy transfer technology.
Tong Li, Tang Liu, Jian Peng, Feng Lin, Wenzheng Xu   +4 more
doaj   +1 more source

Physician‐Scientist Pipeline for Pediatric Rheumatology: The Current Landscape and Future Perspectives

Arthritis Care &Research, EarlyView.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu, Linda T. Hiraki, Mara L. Becker   +2 more
wiley   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Multi-indicator precursor warning method for gas-bearing coal rock fracture based on charge signals

Meitan kexue jishu
To address the challenge of accurate precursor charge signal warning for gas-bearing coal rock dynamic disasters, a comprehensive warning method based on multi-indicator charge signals for gas-bearing coal rock failure is proposed.
Xiaochun XIAO, Xin MA, Xin DING, Yufeng FAN, Wenping ZHANG   +4 more
doaj   +1 more source