Results 71 to 80 of about 470,590 (265)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Phase transition and critical phenomena of charged Einstein–Maxwell-scalar black holes

open access: yesEuropean Physical Journal C: Particles and Fields
We study the phase transition and critical phenomenon of charged black holes in Einstein–Maxwell-scalar (EMs) theory. Through comprehensive analysis of thermodynamic behaviors manifested in $$P-V$$ P - V diagrams, G(T, P) surfaces, and $$C_P$$ C P curves,
Zeming Zhuang, Kun Meng, Hongsheng Zhang
doaj   +1 more source

Anomalous thermo-osmotic conversion performance of ionic covalent-organic-framework membranes in response to charge variations

open access: yesNature Communications, 2022
The development of ionic membranes with a high charge population is critical for realizing efficient thermo-osmotic energy conversion. Here, the authors demonstrated that the thermo-osmotic energy conversion efficiency can be improved by increasing the ...
Weipeng Xian   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Enhancing lung transplantation with ECMO: a comprehensive review of mechanisms, outcomes, and future considerations

open access: yesThe Journal of ExtraCorporeal Technology
Background: Lung transplantation (LTx) is a critical intervention for patients with end-stage lung disease. However, challenges such as donor organ scarcity and post-transplant complications significantly affect its success.
Pervaiz Butt Salman   +20 more
doaj   +1 more source

Criticality in charge-asymmetric hard-sphere ionic fluids

open access: yesPhysical Review E, 2005
25 pages, 14 figures; last update with typos corrected and some added ...
Aqua, Jean-Noël   +2 more
openaire   +5 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Effects of string cloud on Gauss-Bonnet holographic superconductors

open access: yesPhysics Letters B, 2019
The effects of the string cloud on higher-dimensional holographic superconductors in Einstein-Gauss-Bonnet gravity are investigated in the probe limit. The critical temperature is analytically obtained using Sturm-Liouville eigenvalue method.
Cao H. Nam
doaj   +1 more source

Hairy black holes and holographic heat engine

open access: yesNuclear Physics B, 2020
By considering AdS charged black hole in the context of extended thermodynamic as the working substance we use it as a heat engine. We investigate the effect of hairy charge on the evolution of efficiency and Carnot efficiency along with electric charge.
H. Ghaffarnejad   +3 more
doaj   +1 more source

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