Results 61 to 70 of about 470,590 (265)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Unveiling the charge transfer dynamics steered by built-in electric fields in BiOBr photocatalysts

open access: yesNature Communications, 2022
While internal electric fields alter charge-separation dynamics in solar-to-chemical conversions, a greater understanding of such processes is necessary.
Zhishan Luo   +10 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Charging effects and anomalous resistive features of superconducting boron doped diamond films

open access: yesAIP Advances, 2019
Anomalous resistive peaks below the superconducting transition temperature in heavily boron doped nanocrystalline diamond films could have potential application in switching devices, however it’s exact origin is still under study.
Christopher Coleman   +1 more
doaj   +1 more source

The propagation of spiraling elliptic sine soliton in nonlocal nonlinear media

open access: yesResults in Physics, 2018
We study a novel spiraling elliptic sine soliton (SESS) in nonlocal nonlinear media by split-step Fourier method, and find that the profile and phase of such soliton have complicated structures.
Rui Liu, JingZhen Li
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Charge Critical Phenomena in a Field Heterostructure with Two-Dimensional Crystal

open access: yesSolids
The charge properties and regularities of mutual influence of the electro-physical parameters in a metal (M)/insulator (I)/two-dimensional crystal heterostructure were studied. In one case, the transition metal dichalcogenide (TMD) MoS2 was considered as
Alexander L. Danilyuk   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Novel equal area law and analytical charge-electric potential criticality for charged Anti-de Sitter black holes

open access: yesPhysics Letters B, 2019
We study the equal area law and charge-electric potential criticality for the charged Anti-de Sitter black holes. Considering that the black hole charge is a double-valued function of the electric potential, we investigate the equal area law in detail ...
Run Zhou, Shao-Wen Wei
doaj   +1 more source

Home - About - Disclaimer - Privacy