Results 61 to 70 of about 451,002 (267)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Phase transitions and critical behaviour for charged black holes [PDF]

Classical and Quantum Gravity, 2003
LaTeX, 14 pages, 9 eps figures; higher resolution figures available on ...
Carlip, S., Vaidya, S.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Charge Critical Phenomena in a Field Heterostructure with Two-Dimensional Crystal

Solids
The charge properties and regularities of mutual influence of the electro-physical parameters in a metal (M)/insulator (I)/two-dimensional crystal heterostructure were studied. In one case, the transition metal dichalcogenide (TMD) MoS2 was considered as
Alexander L. Danilyuk, Denis A. Podryabinkin, Victor L. Shaposhnikov, Serghej L. Prischepa   +3 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Enhancing lung transplantation with ECMO: a comprehensive review of mechanisms, outcomes, and future considerations

The Journal of ExtraCorporeal Technology
Background: Lung transplantation (LTx) is a critical intervention for patients with end-stage lung disease. However, challenges such as donor organ scarcity and post-transplant complications significantly affect its success.
Pervaiz Butt Salman, Kakar Vivek, Abdulaziz Salman, Razzaq Nabeel, Saleem Yasir, Kumar Arun, Ashiq Fazil, Ghisulal Praveen, Thrush Aaron, Malik Sadaf, Griffin Mairead, Amir Mahanoor, Khan Umar, Salim Ashal, Zoumot Zaid, Mydin Izanee, Aljabery Yazan, Bhatnagar Gopal, Bayrak Yusuf, Obeso Andres, Ahmed Usman   +20 more
doaj   +1 more source

Novel equal area law and analytical charge-electric potential criticality for charged Anti-de Sitter black holes

Physics Letters B, 2019
We study the equal area law and charge-electric potential criticality for the charged Anti-de Sitter black holes. Considering that the black hole charge is a double-valued function of the electric potential, we investigate the equal area law in detail ...
Run Zhou, Shao-Wen Wei
doaj   +1 more source

Anomalous thermo-osmotic conversion performance of ionic covalent-organic-framework membranes in response to charge variations

Nature Communications, 2022
The development of ionic membranes with a high charge population is critical for realizing efficient thermo-osmotic energy conversion. Here, the authors demonstrated that the thermo-osmotic energy conversion efficiency can be improved by increasing the ...
Weipeng Xian, Xiuhui Zuo, Changjia Zhu, Qing Guo, Qing-Wei Meng, Xincheng Zhu, Sai Wang, Shengqian Ma, Qi Sun   +8 more
doaj   +1 more source

Charge Frustration and Quantum Criticality for Strongly Correlated Fermions [PDF]

Physical Review Letters, 2008
5 pages, 4 figures, 1 table; slightly extended version of published ...
Huijse, L., Halverson, J., Fendley, P., Schoutens, K.   +3 more
openaire   +5 more sources

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source