Results 141 to 150 of about 14,518,951 (245)

Threshold fertility for the avoidance of extinction under critical conditions. [PDF]

PLoS One
Cuaresma DCN, Ito H, Arima H, Yoshimura J, Morita S, Okabe T.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Artificial Intelligence in Prehospital Emergency Care: Advancing Triage and Destination Decisions for Time-Critical Conditions. [PDF]

Cureus
Zarei R, Downs MC, Torgerson L.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Quantitative Theory for Critical Conditions of Like-Charge Attraction between Polarizable Spheres. [PDF]

J Chem Theory Comput
Duan Y, Gan Z.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

From Rash Decisions to Critical Conditions: A Systematic Review of Dermatological Presentations in Emergency Departments. [PDF]

Diagnostics (Basel)
Algarni AS, Alshiakh SM, Alghamdi SM, Alahmadi MA, Bokhari AW, Aljubayri SN, Almutairy WM, Alfahmi NM, Samargandi R.   +8 more
europepmc   +1 more source

Market Mix Factors Affecting Thai Tourists' Decision to Use Small and Medium-Sized Hotels Under the Critical Conditions of the COVID-19 Pandemic in Chiang Mai, Thailand

, 2023
Qun L, Leelapattana W, Trakansiriwanich K, Waiapha Y, Sitthikun S.   +4 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Mastering the brain in critical conditions: an update. [PDF]

Intensive Care Med Exp
Robba C, Zanier ER, Lopez Soto C, Park S, Sonneville R, Helbolk R, Sarwal A, Newcombe VFJ, van der Jagt M, Gunst J, Gauss T, Figueiredo S, Duranteau J, Skrifvars MB, Iaquaniello C, Muehlschlegel S, Metaxa V, Sandroni C, Citerio G, Meyfroidt G.   +19 more
europepmc   +1 more source