Results 51 to 60 of about 4,774,455 (278)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The techniques of clinical hypnosis and ‘altered states of consciousness’ in pain and suffering relief, at the end of life.

, 2011
5.3 Hypnosis 257 The techniques of clinical hypnosis and ‘altered states of consciousness’ in pain and suffering relief, at the end of life. Paola Brugnoli Cancer pain and chronic non malignant pain, can have devastating effects on patients’ end of
Brugnoli, Maria Paola
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Covert consciousness in critical care

Intensive Care Medicine
Large-scale epidemiological studies of disorders of consciousness (DoC) including coma are limited. A crowdsourcing approach estimated a point prevalence for coma of 7–31/100.000 and an annual incidence of 135–258/100.000 in the US and the UK, highlighting that acute DoC are an underrecognized medical and socioeconomic emergency [1].
Jan Claassen, Daniel Kondziella, Michael J. Young   +2 more
openaire   +4 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Racism and Mental Health: The Moderating Role of Critical Consciousness for Black Adolescents

Youth
This study examined experiences of individual, institutional, and cultural racism, along with critical consciousness (i.e., critical reflection, critical agency, critical action), and how they are associated with mental health outcomes for Black ...
Elan C. Hope, Alexandrea R. Golden, Nkemka Anyiwo   +2 more
doaj   +1 more source

The limits of consciousness [PDF]

, 2018
Consciousness is essential for one’s normal functioning, including targeted interactions with the surrounding world and with other human beings. At present, many theories and definitions of consciousness coexist, the focus of which can be on the ...
Wolff, Audrey
core  

Before Consciousness

, 2017
Without consciousness we would not have the experientially flavoured world we have, but without the non-conscious we would not have it at all; for we would not be able to breathe, eat, move, walk, feel, mimic, gesture, laugh, etc., and even see, talk ...
Radman, Zdravko
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source