Results 131 to 140 of about 8,410,995 (293)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Du mouvement des cartes SIM aux mobilités touristiques : une analyse de Flux Vision Tourisme comme procédure de quantification

Bulletin de l’Association de Géographes Français
Flux Vision is a commercial product of the mobile network provider Orange, which quantifies the presence and movement of people in a given area based on the signals recorded by the network of antennas of the company.
Valérian Geffroy
doaj   +1 more source

Critique and Contribute: A Practice-Based Framework for Improving Critical Data Studies and Data Science. [PDF]

Big Data, 2017
Neff G, Tanweer A, Fiore-Gartland B, Osburn L.   +3 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Decentering Technology in the Datafied Workplace: Data (In)Justice and Workers’ Experiences of Algorithmic Management in Call Centers in the United Kingdom and Greece

International Journal of Communication
This article makes a key contribution to debates on algorithmic management by bringing together insights from labor process analysis and critical data studies to examine how workers experience and understand injustices related to the introduction of data-
Lina Dencik, Jess Brand, Philippa Metcalfe   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Sustainability powered by digitalization? (Re-)politicizing the debate

Sustainability: Science, Practice, & Policy
As ecological crises escalate, various stakeholders frame digitalization as a key solution for sustainability transformations. Besides incremental optimization, this promise has not materialized yet.
Florian Steig, Pascal D. Koenig, Jens Marquardt, Angela Oels, Jörg Radtke, Rainer Rehak, Sabine Weiland   +6 more
doaj   +1 more source

The Joint NASA/Goddard-University of Maryland Research Program in Charged Particle and High Energy Photon Detector Technology [PDF]

Having recognized at an early stage the critical importance of maintaining detector capabilities which utilize state of the art techniques, a joint program was formulated.

core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source