Results 71 to 80 of about 8,410,995 (293)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

The Paradox of Police Data

open access: yesKULA, 2018
This paper considers the history and politics of ‘police data.’ Police data, I contend, is a category of endangered data reliant on voluntary and inconsistent reporting by law enforcement agencies; it is also inconsistently described and routinely housed
Stacy Wood
doaj   +1 more source

Digital Subjectivation and Financial Markets: Criticizing Social Studies of Finance with Lazzarato [PDF]

open access: yes, 2016
The recently rising field of Critical Data Studies is still facing fundamental questions. Among these is the enigma of digital subjectivation. Who are the subjects of Big Data? A field where this question is particularly pressing is finance.
Christiaens, Tim
core   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

What is critical big data literacy and how can it be implemented?

open access: yesInternet Policy Review, 2020
This paper argues that data literacy today needs to go beyond the mere skills to use data. Instead, it suggests the concept of an extended critical big data literacy that places awareness and critical reflection of big data systems at its centre.
Ina Sander
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Queer Data Studies edited by Patrick Keilty (2024)

open access: yesThe International Journal of Information, Diversity, & Inclusion
IJIDI Book Review, Volume 8, Issue (3/4), 2024.
Travis Wagner
doaj   +1 more source

Nonlinear Collapse in the Semilinear Wave Equation in AdS

open access: yes, 2013
Previous studies of the semilinear wave equation in Minkowski space have shown a type of critical behavior in which large initial data collapse to singularity formation due to nonlinearities while small initial data does not.
Liebling, Steven L.
core   +1 more source

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