Results 91 to 100 of about 24,804,093 (330)
Respiratory ResearchBackground The effects of smoking reduction on the incidence of lung cancer in patients with chronic obstructive pulmonary disease (COPD) are not well known. This study aimed to investigate the effects of changes in smoking habits after COPD diagnosis on
Sun Hye Shin +5 more
doaj +1 more source
Akademisk Kvarter, 2018 This article aims to discuss the role of the dominant critical tradition of design fiction, as well as defending the merits of a pragmatic and strategic view on design fiction, as potentially real solutions.
Thessa Jensen, Peter Vistisen
doaj +1 more source
Why Critical design is useless
, 2017 Critical design is proliferating. According to Raby, this kind of design creates artefacts in order to “challenge narrow assumptions, preconceptions, and givens about the role products play in everyday life” (Raby, 2008, 94). Conceived basically as "useless", the value of critical design “ultimately lies in its ability to valuate: articulate, refuse ...
openaire +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Critical design parameters for garages
Građevinar, 2013 The acceptability, usability, and economic success of garages depend on the quality of their design. Only minimum or even lower requirements are often applied.
Rudolf Eger
doaj +1 more source
Gifts to the Future: Design Reasoning, Design Research, and Critical Design Practitioners
, 2016 Set in the context of a particular orthodoxy about the history of design research over the last 50 years, this opinion piece selectively surveys some of the significant findings from research into what expert design reasoning entails.
J. McDonnell
semanticscholar +1 more source
MIMIC-III, a freely accessible critical care database
Scientific Data, 2016 MIMIC-III (‘Medical Information Mart for Intensive Care’) is a large, single-center database comprising information relating to patients admitted to critical care units at a large tertiary care hospital. Data includes vital signs, medications, laboratory
A. Johnson +9 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Respiratory Research, 2020 Background Idiopathic pulmonary fibrosis (IPF) is a fatal disease that results in poor quality of life due to progressive respiratory symptoms, anxiety, and depression.
Katherine Janssen +3 more
doaj +1 more source