Results 121 to 130 of about 6,768,676 (290)

Transit Thermal Control Design for Galileo Entry Probe for Planet Jupiter [PDF]

open access: yes, 1982
A totally passive design was completed for the thermal control of the Galileo entry probe during its transit to the planet Jupiter. The design utilizes radio isotope heater units, multilayer insulation blankets and a thermal radiator in conjunction with ...
Haverly, George C., Pitts, William
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

‘Bag for Life’ – using multidisciplinary approaches in design pedagogy to develop global citizenship [PDF]

open access: yes, 2010
As the need to integrate approaches to sustainable thinking and global citizenship becomes ever more pressing, a multi disciplinary project has been initiated at Northumbria University's School of Design to address these issues.
Ghassan, Aysar, Rowe, Gill
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

How to design for persistence and retention in MOOCs? [PDF]

open access: yes, 2016
Design of educational interventions is typically carried out following a design cycle involving phases of investigation, conceptualization, prototyping, implementation, execution and evaluation.
Brasher, Andrew   +2 more
core  

Le potentiel éducatif du design fiction dans le développement de la pensée critique

open access: yesReS Futurae
Design fiction is a design practice that uses science fiction to imagine possible futures for technologies. Originally used in the fields of traditional design and human-computer interaction, design fiction offers a real potential for education in a ...
Géraldine Wuyckens
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Production planning systems for cellular manufacturing [PDF]

open access: yes
New product development is one of the most powerful but difficult activities in business. It is also a very important factor affecting final product quality. There are many techniques available for new product development.
Riezebos, J.
core   +1 more source

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