Results 41 to 50 of about 6,768,676 (290)

C1 Esterase Inhibitor (Human) for the Treatment of Acute Hereditary Angioedema

open access: yesClinical Medicine Insights: Blood Disorders, 2011
Hereditary angioedema (HAE) is a relatively rare disease characterized by acute episodes of swelling. These swellings can be disfiguring, painful and life-threatening.
Solange Oliveira Rodrigues Valle   +3 more
doaj   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

The eurozone's critical design flaws [PDF]

open access: yes, 2010
A European Monetary Fund and governance mechanisms with bite would address the problems underlying the current ...
Meyer, Henning
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Criticality meets sustainability: Constructing critical practices in design research for sustainability [PDF]

open access: yes, 2008
Sustainability requires a wider awareness of the changing conditions for design today – rather than focused solely on preserving nature or conserving energy, per se, this opens up for challenging assumptions about relations between design and society and
Mazé, Ramia
core   +1 more source

Restart-Based Fault-Tolerance: System Design and Schedulability Analysis [PDF]

open access: yes, 2017
Embedded systems in safety-critical environments are continuously required to deliver more performance and functionality, while expected to provide verified safety guarantees.
Abdi, Fardin   +3 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Getting it Right: Lessons Learned in Applying a Critical Artefact Approach [PDF]

open access: yes, 2009
“Critical artefacts”, the products of critical design (Dunne 1999), prompt reflection rather than satisfy obvious user needs. The author is developing an instrumental use of critical artefacts as part of a human-centred design process.
Bowen, Simon
core  

Methodology for standard cell compliance and detailed placement for triple patterning lithography [PDF]

open access: yes, 2013
As the feature size of semiconductor process further scales to sub-16nm technology node, triple patterning lithography (TPL) has been regarded one of the most promising lithography candidates.
Gao, Jhih-Rong   +3 more
core   +1 more source

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