Results 41 to 50 of about 1,889,397 (293)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Kondo proximity effect: How does a metal penetrate into a Mott insulator?
, 2008 We consider a heterostructure of a metal and a paramagnetic Mott insulator using an adaptation of dynamical mean field theory to describe inhomogeneous systems. The metal can penetrate into the insulator via the Kondo effect.
A. Georges +5 more
core +1 more source
THEORY OF CRITICAL DISTANCES AND THE THICKNESS OF THE SURFACE LAYER
, 2023 The theory of critical distances is based on the strength of materials L, which is given by its strength properties KIc and σ0. We have shown that the thickness of the surface layer R(I) is equal to the nanocrack length Lnm. We have shown that there is a relationship between L and Lnm: L = 104 Lnm = 104 R(I) ≈ 10-5 М/ρ.
Berdibekov, A.T. +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Quantum structural phase transition in chains of interacting atoms
, 2010 A quasi one--dimensional system of trapped, repulsively interacting atoms (e.g., an ion chain) exhibits a structural phase transition from a linear chain to a zigzag structure, tuned by reducing the transverse trap potential or increasing the particle ...
Fishman, Shmuel +2 more
core +1 more source
Notched multiaxial fatigue of Al7050-T7451: on the need for an equivalent process zone size [PDF]
Fracture and Structural Integrity, 2017 The aim of this work is to investigate stress gradient effects on the fatigue life estimation of notched Al 7050-T7451 specimens under combined torsion and push-pull loading conditions.
J.L.A Ferreira +2 more
doaj +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Criticality in inhomogeneous magnetic systems: Application to quantum ferromagnets
, 2007 We consider a $\phi^4$-theory with a position-dependent distance from the critical point. One realization of this model is a classical ferromagnet subject to non-uniform mechanical stress.
A. I. Larkin +8 more
core +1 more source
Quantum geometry of 2d gravity coupled to unitary matter [PDF]
, 1996 We show that there exists a divergent correlation length in 2d quantum gravity for the matter fields close to the critical point provided one uses the invariant geodesic distance as the measure of distance.
Akopov +50 more
core +3 more sources
Gestalt Theory, 2019 The author exemplifies the congruency of essential foundations between the critical realism of the Berlin School of Gestalt Psychology (Gestalt theory) and Nicolai Hartmann’s Critical Ontology.
Walter Hans-Jürgen P.
doaj +1 more source