Results 91 to 100 of about 1,907,456 (303)

Digital Edition and Critical Edition

open access: yesAnuario Lope de Vega, 2014
Presentation of the volume with a brief state of the art on the critical digital edition of our classic theatrical texts and a short summary of the articles.
openaire   +1 more source

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Demosthenes, "Fourth Philippic": new critical edition [PDF]

open access: yes, 2015
Presentamos una nueva edición crítica del la Cuarta Filípica de Demóstenes, en la que por primera vez incorporamos sistemáticamente el testimonio de un buen número de manuscritos recentiores, especialmente hispánicos, además del de las ediciones aldinas ...
Hernández Muñoz, Felipe
core   +2 more sources

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

Crossing Brooklyn Ferry: An Online Critical Edition

open access: yesRIDE, 2017
Jesse Merandy’s legacy project, Crossing Brooklyn Ferry: An Online Critical Edition (2008-09), presents new avenues for reading and studying American poet Walt Whitman’s iconic work.
Mellissa Hinton
doaj   +1 more source

The Many Roles of an Academic Surgeon [PDF]

open access: yes, 2017
One of our most important responsibilities is training the next generation of fellows, residents, medical students, and undergraduate students aspiring to a career in medicine.
Yeo, MD, FACS, Charles J.
core   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Tendencias en la edición crítica de textos latinos medievales [PDF]

open access: yes, 2006
En esta nota, reviso distintos aportes de ediciones críticas\ud recientes de textos medievales latinos, con el propósito de señalar ciertas\ud tendencias que paulatinamente confieren originalidad a la empresa y la\ud apartan por fin de la edición crítica
Higashi, Alejandro
core   +2 more sources

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong   +13 more
wiley   +1 more source

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