Results 81 to 90 of about 1,907,456 (303)
Advanced Science, EarlyView.ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
[Review of] Langston Hughes. The Big Sea: An Autobiography [PDF]
, 1989 In the last ten years a number of critical studies on the Harlem Renaissance have been published, and these in turn have sparked a revival of interest in the cultural, political, and social activities that took place during the ten-year period in ...
Deck, Alice A.
core +1 more source
Advanced Science, EarlyView.The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen +15 more
wiley +1 more source
Perspectives MédiévalesAround 1396, Francesc Eiximenis, a main figure of Franciscanism in the Crown of Aragon during the 14th and 15th centuries, wrote the Llibre de les dones.
Laura Baldacchino
doaj +1 more source
Uberzeugender Beweis aus der Vernunft von der Unsterblichkeit sowohl der Menschen Seelen insgemein, als besonders der Kinder-Seelen [PDF]
, 2017 Israel Gottlieb Canz’s Uberzeugender Beweiß, first published in 1741 and reprinted here in its second, expanded edition stands as his most influential discussion of the soul’s immortality, with one contemporary pronouncing it to be “one of the best ...
Canz, Israel Gottlieb, Dyck, Corey W.
core
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Meluzyna: dawna literatura i kultura, 2016 This paper is a critical edition of “Lament of the Death of Honourable Lady Katarzyna Branicka” (Treny na śmierć Jej Mości Paniej Katarzyny Branickiej, starościnej niepołomskiej) by Jan Achacy Kmita. The preface introduces the readers to the
Angelika Pełka
doaj +1 more source
Advanced Science, EarlyView.Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor
Advanced Science, EarlyView.Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang +4 more
wiley +1 more source
Revista Galega de Filoloxía, 2017 This article constitutes a historical and critical review of the ecdotic work carried out in the field of Galician-Portuguese secular lyric poetry since the 1960s, the period in which the so-called “Italian school” began its activity.
Mariña Arbor Aldea
doaj +1 more source