Results 61 to 70 of about 144,086 (256)

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye   +9 more
wiley   +1 more source

Itinerarî peninsulari di Amico e Amelio. Con una versione inedita della «Vita» latina (Philadelphia, PSUL Codex 313)

open access: yesCarte Romanze, 2015
L’articolo studia la fortuna italiana medievale della Vita Amici et Amelii carissimorum, che narra la storia dei due cavalieri identici nell’aspetto e pronti ai piú grandi sacrifici l’uno per l’altro, indissolubilmente uniti in vita e dopo la morte.
Luca Sacchi
doaj   +1 more source

Per l’edizione dell’Asino d’oro boiardesco. Escussione completa dei testimoni

open access: yesAnnali Online dell'Università di Ferrara. Sezione Lettere, 2022
The present article aims to provide the full collation between the surviving witnesses of Matteo Maria Boiardo’s Asino d’oro, on which the recent critical edition is based. A detailed description of the witnesses containing this vernacular translation of
Matteo Favaretto
doaj   +1 more source

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Le tenzoni di Pero Garcia Burgalés. Edizione critica e problemi attributivi

open access: yesCarte Romanze, 2013
L’articolo presenta l’edizione critica, annotata e fornita di traduzione, delle due tenzoni in cui è coinvolto il trovatore galego-portoghese Pero Garcia Burgalés.
Simone Marcenaro
doaj   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang   +9 more
wiley   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

open access: yesAdvanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li   +5 more
wiley   +1 more source

Edycja krytyczna Trenów na śmierć Jej Mości Paniej Katarzyny Branickiej, starościnej niepołomskiej Jana Achacego Kmity

open access: yesMeluzyna: dawna literatura i kultura, 2016
This paper is a critical edition of “Lament of the Death of Honourable Lady Katarzyna Branicka” (Treny na śmierć Jej Mości Paniej Katarzyny Branickiej, starościnej niepołomskiej) by Jan Achacy Kmita. The preface introduces the readers to the
Angelika Pełka
doaj   +1 more source

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