Results 141 to 150 of about 5,030,445 (248)

Investigations of spin textures at small length and short timescales with neutron, x-ray, and optical methods. [PDF]

Sci Adv
Fischer P, Broholm C, Tam CC, Wilson SD, Rasing T, Kimel AV.   +5 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Observation of conformal field theory spectra in a quantum simulator. [PDF]

Nature
Sun X, Le Y, Naus S, Tsai RB, Picard LRB, Murciano S, Knap M, Alicea J, Endres M.   +8 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Glottal Flow Derivative Modeling With The

, 2007
This paper discusses a method for estimating glottal flow derivative model parameters using the wavelet-smoothed excitation. The excitation is first estimated using the Weighted Recursive Least Squares with Variable Forgetting Factor algorithm.
Wavelet Smoothed Excitation
core  

Machine learning-enhanced fluorescence signal processing of carbon quantum dots for high-accuracy chemical sensing. [PDF]

RSC Adv
Sayed BT, Shukla MB, Sharma S, Shaaban Z, Singhal D, Nematov O, Sapaev I, Alghazali T, Smerat A, Bayatinia S.   +9 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Conceptual Design and Electromagnetic-Thermal Coupling Analysis of Superconducting Current-Limiting Reactor Under Self-Triggered Built-In Magnetic Field Excitation. [PDF]

Materials (Basel)
Yu Q, Xu H, Chen X, Wang B, Zhao H, Yang J, Xu Q, Qing K.   +7 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

DIRAS2 as a key intermediate molecule joining with ferroptosis and neuronal excitation/inhibition (E/I) balance in epilepsy. [PDF]

Genes Dis
Peng C, Mao X.
europepmc   +1 more source