Results 61 to 70 of about 294,004 (295)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Scaling laws at the critical point

, 2006
There are two independent critical exponents that describe the behavior of systems near their critical point. However, at the critical point only the exponent $\eta$, which describes the decay of the correlation function, is usually discussed.
Davatolhagh, S.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Interplay of quantum and classical fluctuations near quantum critical points

, 2011
For a system near a quantum critical point (QCP), above its lower critical dimension $d_L$, there is in general a critical line of second order phase transitions that separates the broken symmetry phase at finite temperatures from the disordered phase ...
A Paduan-Filho, A Saguia, AA Aczel, AJ Millis, AL Fetter, AP Young, BA Jones, D Reyes, D-X Yao, F Evers, H Caldas, HV Löhneysen, J Flouquet, JA Hertz, JC Guillou Le, JC Guillou Le, KG Wilson, KG Wilson, L Yin, LS Goldner, M Hasenbusch, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, MA Continentino, Mucio Amado Continentino, P Pfeuty, PF Bedaque, Q Si, R Jullien, R Reisser, RR Santos dos, S Sachdev, S Sachdev, T Moriya, T Moriya, VS Zapf, W Janke, Y Kohama   +44 more
core   +1 more source

Critical speeding-up in a local dynamics for the random-cluster model [PDF]

, 2007
We study the dynamic critical behavior of the local bond-update (Sweeny) dynamics for the Fortuin-Kasteleyn random-cluster model in dimensions d=2,3, by Monte Carlo simulation.
A. D. Sokal, Alan D. Sokal, D. Stauffer, G. Grimmett, G. F. Lawler, O. Schramm, P. Di Francesco, P. W. Kasteleyn, R. B. Potts, R. J. Baxter, S. Rohde, Timothy M. Garoni, Youjin Deng   +12 more
core   +2 more sources

On a p-Laplacian system with critical Hardy–Sobolev exponents and critical Sobolev exponents [PDF]

Ukrainian Mathematical Journal, 2012
In this paper, the existence results of positive solutions for the semiliner elliptic system \[ \begin{cases} -\text{div} (|\nabla u_i|^{p-2} \nabla u_i) - \mu \frac{|u_i|^{p-2}u_i}{|x|^p} \\ = \frac{1}{p^*} F_{u_i}(u_1,\ldots,u_k) + \frac{|u_i|^{p^*(t)-2}u_i}{|x|^t} + \lambda \frac{|u_i|^{p-2}u_i}{|x|^s}, \quad x \in \Omega, \\ u_i=0 \quad \text{on} \;
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Schrodinger-Poisson systems with singular potential and critical exponent

Electronic Journal of Differential Equations, 2020
In this article we study the Schrodinger-Poisson system $$\displaylines{ -\Delta u +V(|x|)u+\lambda\phi u = f(u), \quad x\in\mathbb{R}^3, \cr -\Delta \phi =u^2, \quad x\in\mathbb{R}^3, }$$ where V is a singular potential with the parameter $\alpha ...
Senli Liu, Haibo Chen, Zhaosheng Feng
doaj  

Dynamic Critical approach to Self-Organized Criticality

, 2005
A dynamic scaling Ansatz for the approach to the Self-Organized Critical (SOC) regime is proposed and tested by means of extensive simulations applied to the Bak-Sneppen model (BS), which exhibits robust SOC behavior.
Alejandro F. Rozenfeld, Ezequiel V. Albano, H. J. Jensen, Karina Laneri, P. Bak   +4 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source