Results 41 to 50 of about 4,696,970 (248)

The critical exponent of the Arshon words [PDF]

, 2010
Generalizing the results of Thue (for n = 2) [Norske Vid. Selsk. Skr. Mat. Nat. Kl. 1 (1912) 1–67] and of Klepinin and Sukhanov (for n = 3) [Discrete Appl. Math.
Dalia Krieger, Krieger, Dalia
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Global Persistence Exponent for Critical Dynamics

, 1996
International audienceA 'persistence exponent\' $\\theta$ is defined for nonequilibrium critical phenomena. It describes the probability, $p(t) \\sim t^{-\\theta}$, that the global order parameter has not changed sign in the time interval $t$ following a
Sire, Clément, Bray, A. J., Majumdar, S. N., Cornell, S. J.   +3 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Critical exponent analysis of Cu-doped SrRuO3 perovskite: SrRu0.925Cu0.075O3

Results in Surfaces and Interfaces
As an itinerant ferromagnet with strong spin-orbit coupling and high magnetocrystalline anisotropy, the SrRuO3 is ideal for studying correlated magnetism, while doping at Ru-site enables precise control over its electronic and magnetic properties.
Kiruthiga Devi B., Ajith Nix E.S.R., Praveen Palabindela, Jaivardhan Sinha, Bhaskar Chandra Behera   +4 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Blow-up theorems of Fujita type for a semilinear parabolic equation with a gradient term

Advances in Difference Equations, 2018
This paper deals with the existence and non-existence of the global solutions to the Cauchy problem of a semilinear parabolic equation with a gradient term.
Yang Na, Mingjun Zhou, Xu Zhou, Guanming Gai   +3 more
doaj   +1 more source

Critical Exponent for the Acyclic Chromatic Number of Random Graphs [PDF]

, 2023
In this paper we study acyclic colouring in the random subgraph $\mathit{G}$ of the complete graph $\mathit{K}_n$ on $\mathit{n}$ vertices where each edge is present with probability $\mathit{p}$; independent of the other edges.
Ganesan, Ghurumuruhan
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source