Results 71 to 80 of about 293,756 (338)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Critical speeding-up in a local dynamics for the random-cluster model [PDF]

, 2007
We study the dynamic critical behavior of the local bond-update (Sweeny) dynamics for the Fortuin-Kasteleyn random-cluster model in dimensions d=2,3, by Monte Carlo simulation.
A. D. Sokal, Alan D. Sokal, D. Stauffer, G. Grimmett, G. F. Lawler, O. Schramm, P. Di Francesco, P. W. Kasteleyn, R. B. Potts, R. J. Baxter, S. Rohde, Timothy M. Garoni, Youjin Deng   +12 more
core   +2 more sources

First and second critical exponents for an inhomogeneous Schrödinger equation with combined nonlinearities [PDF]

, 2022
Munirah Alotaibi, Mohamed Jleli, Bessem Samet, Calogero Vetro   +3 more
openalex   +1 more source

Corrigendum to “The critical exponent functions”

Comptes Rendus. Mathématique
We give a corrigendum to our paper [1] entitled “The critical exponent functions”.
Corona, Dario, Della Corte, Alessandro
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Homological dimension and critical exponent of Kleinian groups [PDF]

, 2007
We prove that the relative homological dimension of a Kleinian group G does not exceed 1 + the critical exponent of G. As an application of this result we show that for a geometrically finite Kleinian group G, if the topological dimension of the limit ...
Kapovich, Michael
core   +4 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

The Critical Exponent $\theta'$ in Spin Glasses

, 1999
Short-time dynamic scaling behavior of the 3D $\pm J$ Ising spin glass is studied by Monte Carlo methods. Starting the replicas with independent initial configurations with a small pseudo magnetization, the dynamic evolution of the overlap q(t) between ...
Luo, H. J., Schuelke, L., Zheng, B.
core   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Schrodinger-Poisson systems with singular potential and critical exponent

Electronic Journal of Differential Equations, 2020
In this article we study the Schrodinger-Poisson system $$\displaylines{ -\Delta u +V(|x|)u+\lambda\phi u = f(u), \quad x\in\mathbb{R}^3, \cr -\Delta \phi =u^2, \quad x\in\mathbb{R}^3, }$$ where V is a singular potential with the parameter $\alpha ...
Senli Liu, Haibo Chen, Zhaosheng Feng
doaj