Results 81 to 90 of about 5,079,022 (381)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Dynamic Critical approach to Self-Organized Criticality
, 2005 A dynamic scaling Ansatz for the approach to the Self-Organized Critical (SOC) regime is proposed and tested by means of extensive simulations applied to the Bak-Sneppen model (BS), which exhibits robust SOC behavior.
Alejandro F. Rozenfeld +4 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
On the critical exponent of transversal matroids
Journal of Combinatorial Theory, Series B, 1984 AbstractIt is shown that loopless transveral matroids have critical exponent at most 2.
openaire +3 more sources
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Designing and Delivering Effective Faculty Development With the Adult Learner in Mind
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT University faculty are busy professionals tasked with many different responsibilities. While they certainly care about student success, their expertise is generally discipline‐specific and strategies for effective and engaging teaching are developed in the classroom along the way.
Nancy V. Winfrey
wiley +1 more source
Universality versus nonuniversality in asymmetric fluid criticality
Condensed Matter Physics, 2013 Critical phenomena in real fluids demonstrate a combination of universal features caused by the divergence of long-range fluctuations of density and nonuniversal (system-dependent) features associated with specific intermolecular interactions ...
M.A. Anisimov
doaj +1 more source
The critical exponent of the Arshon words [PDF]
RAIRO - Theoretical Informatics and Applications, 2010 11 ...
openaire +3 more sources
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Nontraditional students represent a substantial number and significant percentage of students in higher education. While these adult learners have similarities, they also span 50+ years with generational differences. At the same time, online learning is on the rise, offering opportunities and challenges for nontraditional students and those ...
Brittany Hyden, Catherine A. Cherrstrom
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This autobiographical article recounts a White woman's efforts to establish a center for teaching and learning (CTL) in a large HBCU in the southern part of the United States. She describes the ways in which tenets of critical feminism, feminist pedagogies, and adult learning and development informed her approach to faculty development.
Audrey Dentith
wiley +1 more source