Results 71 to 80 of about 157,296 (287)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Small perturbations of critical nonlocal equations with variable exponents

Demonstratio Mathematica, 2023
In this article, we are concerned with the following critical nonlocal equation with variable exponents: (−Δ)p(x,y)su=λf(x,u)+∣u∣q(x)−2uinΩ,u=0inRN\Ω,\left\{\begin{array}{ll}{\left(-\Delta )}_{p\left(x,y)}^{s}u=\lambda f\left(x,u)+{| u| }^{q\left(x)-2}u&
Tao Lulu, He Rui, Liang Sihua
doaj   +1 more source

Continuously varying critical exponents in long-range quantum spin ladders

SciPost Physics, 2023
We investigate the quantum-critical behavior between the rung-singlet phase with hidden string order and the Néel phase with broken SU(2)-symmetry in quantum spin ladders with algebraically decaying unfrustrated long-range Heisenberg interactions.
Patrick Adelhardt, Kai Phillip Schmidt
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Lyapunov exponents and phase transition of Hayward AdS black hole

European Physical Journal C: Particles and Fields
In this paper, we study the relationship between the phase transition and Lyapunov exponents for 4D Hayward anti-de Sitter (AdS) black hole. We consider the motion of massless and massive particles around an unstable circular orbit of the Hayward AdS ...
Naba Jyoti Gogoi, Saumen Acharjee, Prabwal Phukon   +2 more
doaj   +1 more source

The Ising Spin Glass in dimension four

, 2015
The critical behaviors of the bimodal and Gaussian Ising spin glass (ISG) models in dimension four are studied through extensive numerical simulations, and from an analysis of high temperature series expansion (HTSE) data of Klein {\it et al.} (1991 ...
Campbell, I. A., Lundow, P. H.
core   +3 more sources

Critical behavior of hadronic matter: Critical-point exponents [PDF]

Physical Review D, 1979
In statistical physics, the principle of maximum entropy provides conditions on the singular behavior of thermodynamic functions near a critical point, in the form of inequalities for the critical-point exponents. Hadronic matter, when described by an exponentially rising density of states (dual resonance, statistical bootstrap models), exhibits ...
openaire   +2 more sources

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Off-critical parafermions and the winding angle distribution of the O($n$) model

, 2012
Using an off-critical deformation of the identity of Duminil-Copin and Smirnov, we prove a relationship between half-plane surface critical exponents $\gamma_1$ and $\gamma_{11}$ as well as wedge critical exponents $\gamma_2(\alpha)$ and $\gamma_{21 ...
de Gier, Jan, Guttmann, Anthony J., Lee, Alexander, Price, Andrew Elvey   +3 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source