Results 21 to 30 of about 3,001 (111)

Coping Practices of Small‐ and Medium‐Sized Enterprises Facing Power Asymmetry in Digital Platform Business

open access: yesStrategic Change, EarlyView.
ABSTRACT Digital platform (DP) enterprises have risen to the top of the global economy by inverting traditional business models. They earn money through matchmaking, transaction facilitation, and efficient orchestration of other stakeholders' resources.
Lukas R. G. Fitz, Jochen Scheeg
wiley   +1 more source

Testing the Collective Properties of Small-World Networks through Roughness Scaling

open access: yes, 2003
Motivated by a fundamental synchronization problem in scalable parallel computing and by a recent criterion for ``mean-field'' synchronizability in interacting systems, we study the Edwards-Wilkinson model on two variations of a small-worldnetwork.
A. Barrat   +10 more
core   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

From Stability to Chaos: A Complete Classification of the Damped Klein‐Gordon Dynamics

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT We investigate the transition between stability and chaos in the damped Klein‐Gordon equation, a fundamental model for wave propagation and energy dissipation. Using semigroup methods and spectral criteria, we derive explicit thresholds that determine when the system exhibits asymptotic stability and when it displays strong chaotic dynamics ...
Carlos Lizama   +2 more
wiley   +1 more source

Reduced-order Description of Transient Instabilities and Computation of Finite-Time Lyapunov Exponents

open access: yes, 2017
High-dimensional chaotic dynamical systems can exhibit strongly transient features. These are often associated with instabilities that have finite-time duration.
Arnold V. I.   +4 more
core   +1 more source

Numerical Investigation of a Diffusive SIR Model: Focus on Positivity Preservation

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this paper, we consider a system of semilinear partial differential equations (PDEs) representing a spatially extended SIR epidemic model. A brief analytical investigation of the well‐posedness and positivity of the solutions is provided in the appendix, while the main focus is on the numerical treatment of the model.
Rahele Mosleh   +2 more
wiley   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

open access: yesRespirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Beyond the next step: A multi‐criteria generative validation framework for step selection functions

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract Step‐selection functions (SSFs), typically fitted using step‐selection analysis (SSA) or integrated step‐selection analysis (iSSA) are widely used to infer habitat selection and movement kernels from high‐frequency telemetry data, but most standard validation tools focus on one‐step‐ahead prediction and do not guarantee that fitted models ...
Aurélien Nicosia
wiley   +1 more source

Exact solution of the van der Waals model in the critical region

open access: yes, 2015
The celebrated van der Waals model describes simple fluids in the thermodynamic limit and predicts the existence of a critical point associated to the gas-liquid phase transition.
Barra, Adriano, Moro, Antonio
core   +1 more source

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu   +4 more
wiley   +1 more source

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