Results 21 to 30 of about 106 (94)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
SDFs from Unoriented Point Clouds using Neural Variational Heat Distances
Computer Graphics Forum, EarlyView.We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from unoriented point clouds. We first compute a small time step of heat flow (middle) and then use its gradient directions to solve for a neural SDF (right). Abstract We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from ...
Samuel Weidemaier +5 more
wiley +1 more source
Random Carbon Tax Policy and Investment Into Emission Abatement Technologies
Mathematical Finance, EarlyView.ABSTRACT We analyze the problem of a profit‐maximizing electricity producer, subject to carbon taxes, who decides on investments into CO2$\rm CO_2$ abatement technologies. We assume that the carbon tax policy is random and that the investment in the abatement technology is divisible, irreversible, and subject to transaction costs.
Katia Colaneri +2 more
wiley +1 more source
Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Advanced Science, Volume 13, Issue 31, 4 June 2026.This study reports on the physical implementation of optical material‐based neural processing using long‐persistent luminescence as memory‐retention and nonlinear optical material. The system performs optical‐domain preprocessing with opto‐electronic interfaces for stimulus delivery and readout, enabling real‐time demonstrations including Pong gameplay
Sangwon Wi, Yunsang Lee
wiley +1 more source
Semilinear PDEs on self-similar fractals
, 1999 A Laplacian may be defined on self-similar fractal domains in terms of a suitable self-similar Dirichlet form, enabling discussion of elliptic PDEs on such domains.
Falconer, Kenneth John
core
Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1465-1480, June 2026.ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal +2 more
wiley +1 more source
From Stability to Chaos: A Complete Classification of the Damped Klein‐Gordon Dynamics
Mathematical Methods in the Applied Sciences, Volume 49, Issue 9, Page 9696-9708, June 2026.ABSTRACT We investigate the transition between stability and chaos in the damped Klein‐Gordon equation, a fundamental model for wave propagation and energy dissipation. Using semigroup methods and spectral criteria, we derive explicit thresholds that determine when the system exhibits asymptotic stability and when it displays strong chaotic dynamics ...
Carlos Lizama +2 more
wiley +1 more source
Gram Decay and Intrinsic Dimensions of Krylov Subspaces
Numerical Linear Algebra with Applications, Volume 33, Issue 3, June 2026.ABSTRACT Krylov subspace methods solve large sparse linear systems Ax=b$$ Ax=b $$ by building a sequence of polynomial approximations to A−1b$$ {A}^{-1}b $$ from successive matrix‐vector products. In finite precision, the number of numerically independent directions that can be extracted from this sequence is bounded by the intrinsic information ...
Stephen J. Thomas
wiley +1 more source
Building a Digital Twin for Material Testing: Model Reduction and Data Assimilation
Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 2, June 2026.ABSTRACT The rapid advancement of industrial technologies, data collection, and handling methods has paved the way for the widespread adoption of digital twins (DTs) in engineering, enabling seamless integration between physical systems and their virtual counterparts.
Rubén Aylwin +5 more
wiley +1 more source