Results 71 to 80 of about 2,327 (266)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Wavelength dependency of the critical flicker-fusion frequency:Therapeutic 40 Hz light source in alzheimer’s disease

, 2021
The use of controlled temporal modulated light increased in prominence since the LEDs invention, e.g., in computer monitors and light therapy devices. The benefits of using LEDs compared to old incandescent light bulbs range from environmental load to ...
Carstensen, Marcus S., Kjær, Troels W., Thorning-Schmidt, Martin W., Petersen, Paul Michael, Agger, Mikkel, Broeng, Jes, Nguyen, N. Mai   +6 more
core   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Effect of Foot Reflexology on Cognitive Function in Healthy Individuals: A Randomized Controlled trial

Journal of Acupuncture Research
Background: Reflexology is a timeless healing art rooted in ancient Chinese, Egyptian, and Native American cultures. Cognition refers to the brain’s capacity to gather, interpret, retain, and recall information.
B. Snekha, Venkatalakshmi Saravanan, R. Thirumalaivasan, S. Thannmadhi, S. Sneha, N. D. Sournamaalya, N. Mangaiarkarasi, A. Mooventhan   +7 more
doaj   +1 more source

Sustainable Synaptic Device with Two‐Dimensional Ferroelectric Materials for Neuromorphic Computing

Advanced Science, EarlyView.
α‐In2Se3 based FeSFETs can be utilized as sustainable devices through polarization switching governed by both out‐of‐plane and in‐plane polarizations. Upon reaching a fatigued state, current annealing enabled by conductance modulation can significantly enhance the endurance of FeSFETs.
Jaewook Yoo, Seokjin Oh, Minah Park, Jong Min Song, Hongseung Lee, Seohyeon Park, Sojin Jung, Seongbin Lim, Soohyun Lim, Dongsun Shin, Ji Won Heo, TaeWan Kim, Hagyoul Bae   +12 more
wiley   +1 more source

Critical flicker fusion frequency as vision fatigue indicator

, 2015
Bakalaura darbs uzrakstīts latviešu valodā, uz 32 lapaspusēm, satur 20 attēlus, 4 tabulas, atsaucas uz 17literatūras avotiem un ietver 2 pielikumus.
Valpētere, Diāna
core  

Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer

Advanced Science, EarlyView.
A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang, Jinlei Jiang, Zhengting Wang, Shuqi Liu, Wei Wang, Xi Chen, Qirui Zhao, Xinyuan Cui, Cheng Zhou, Shengsheng Cui, Daxiang Cui   +10 more
wiley   +1 more source

Functional comparison between critical flicker fusion frequency and simple cognitive tests in subjects breathing air or oxygen in normobaria.

, 2013
Measurement of inert gas narcosis and its degree is difficult during operational circumstances, hence the need for a reliable, reproducible and adaptable tool.
Balestra, Costantino, Germonpre, P., Rozloznik, Miroslav, Germonpré, Peter, Hemelryck, W., Balestra, C., Lafere, P., Lafere, Pierre, Rozloznik, M., Hemelryck, Walter   +9 more
core  

The Apparatus to Measure the Multi-point Critical Flicker Fusion Frequency (MCFF)

, 1984
In this paper, we mentioned the apparatus developed to measure CFFs at the various point of the retina. Eleven CFFs measured at the central retina of both eyes (used usually} simultaneously, at the central retina of each eye separately, and at four ...
Miyake, Hirofumi, Kikuchi, Susumu, Ogata, Masana, Osaki, Hirokazu   +3 more
core   +1 more source