Results 141 to 150 of about 1,563,368 (312)

Designing flow and temperature uniformities in a parallel microchannels reactor

, 2014
A design methodology is proposed to maintain gas and liquid flow nonuniformities below an acceptable limit in a parallel micro/millichannels reactor by determining the maximum allowed temperature deviation in each part of the reactor.
Nijhuis, TA Xander = Alexander, Al-Rawashdeh, MIM Ma'moun, Patil, N.G., T. A. Nijhuis, Patil, NG Narendra, Hessel, V., Narendra G. Patil, Evgeny V. Rebrov, Yue, F., Al-Rawashdeh, M.I.M., Jaap C. Schouten, Yue, F, Schouten, J.C., Volker Hessel, Rebrov, E.; id_orcid, Schouten, J C, Rebrov, E., Ma'moun Al‐Rawashdeh, Fangyuan Yue, Rebrov, E Evgeny, Hessel, V, Nijhuis, T.A.   +21 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Modeling of critical sand-carrying flow rate of gas-liquid-solid three-phase flow in an inclined pipe

Results in Engineering
The critical sand-carrying velocity of gas-liquid-solid three-phase flow is widely applied in natural gas extraction, such as coalbed methane wells and tight gas wells.
Guowei Wang, Yong Zhang, Junwei Sun, Qi Xia, Manlai Zhang, Ruiquan Liao   +5 more
doaj   +1 more source

Critical flow and dissipation in a quasi-one-dimensional superfluid. [PDF]

Sci Adv, 2015
Duc PF, Savard M, Petrescu M, Rosenow B, Del Maestro A, Gervais G.   +5 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Similarities and differences between flow boiling in microchannels and pool boiling

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Kandlikar, SG   +1 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

The effect of liquid spreading due to micro-structures of flow boiling critical heat flux

, 2019
The effect of a micro-structured Zirlo surface on the internal flow boiling critical heat flux (CHF) was examined under atmospheric pressure conditions for water.
Kim, J, Chan Lee, Ho Seon Ahn, Kim, MH, Soon Ho Kang   +4 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Analysis of Nozzle Flow under Low Pressure Non-Critical Flow in Coalbed Methane Well

Shiyou jixie, 2020
The law of nozzle flow is of great significance for establishing the law of reservoir and wellbore pressure and gas well production. In view of this, according to the theoretical calculation model of the on-site nozzle, the theoretical calculation model ...
He Dong, Song Yunfei, Han Shuai, Shi Huailong, Zhang Fenna   +4 more
doaj